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The X Factor judge - who picked the double act from her groups category to leave during the first live final - wants viewers to bring them back to replace Frankie Cocozza, who was axed from the show on Tuesday after he broke show rules by boasting about drug use.
Viewers can throw a lifeline to one of the four acts who were ditched from the show by their own mentors, with 2 Shoes competing with Amelia Lily, James Michael and Jonjo Kerr.
ITV and show producers TalkbackThames and Syco have said the profits from the phonecalls - amounting to at least 22p per call - will go to Help For Heroes.
Phone lines opened at 4pm today (Friday) and close during the show on Saturday, which begins at 8.15pm, with call terms at www.itv.com/terms.
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