The West End's smallest theatre is to host three of the biggest stars of the stage.

All That Fall, a radio play by Samuel Beckett that has never been performed in London before, will be performed at the 70-seat Jermyn Street Theatre, with Trevor Nunn directing Eileen Atkins and Michael Gambon in the lead roles.

Trevor Nunn said: "For many years I have been hoping to present Samuel Beckett's extraordinary radio play All That Fall on stage.

"The Jermyn Street Theatre is the perfect intimate space for this unique project, as I attempt to recreate the studio circumstances for which the play was written.

"Most excitingly, this rare staging of a little-known Beckett masterpiece has attracted the involvement of two world-famous actors, Eileen Atkins and Michael Gambon, to play the leading parts of Mrs and Mr Rooney."

The play tells the story of the elderly Mrs Rooney, who is on her way to meet her blind husband at a railway station to guide him home and finds herself encountering other people on the way.

Nunn added: "My hope is that audiences won't try to find and read the play beforehand, but come to it as if it is a new work about which they know almost nothing. The impact of this play will then be at its most devastating."

Gene David Kirk, artistic director of Jermyn Street Theatre, said: "This is a quadruple coup for Jermyn Street Theatre.

"A rare staging by one of the most influential figures of 20th century theatre directed by one of the most lauded directors of his generation and starring two of the greatest actors working today.

"Any one of those ingredients would have been massive for a theatre of our size, but to have them together makes us immensely proud and excited."

The run will start on 9 October and finish on 3 November.