Steve Clarke has been appointed as West Brom head coach, the club have announced on their website.
Albion have been searching for a new manager since Roy Hodgson was announced as England boss ahead of the European Championship.
And former Chelsea assistant manager and Liverpool coach Clarke has now been handed the reins, signing a two-year contract at the Hawthorns.
"I'm absolutely delighted to be given this opportunity," Clarke told wba.co.uk.
"Becoming a head coach in my own right has always been an ambition of mine and I feel I have served my apprenticeship.
"I've done everything I could as an assistant.
"I'm delighted West Bromwich Albion have given me the chance to make that progression and I'm determined to make the most of it."
Clarke's departure from Liverpool was only confirmed on Wednesday, although he had offered his resignation last month when Kenny Dalglish was sacked.
But having also worked under the likes of Jose Mourinho and the late Sir Bobby Robson - contributing to winning two Premier League titles, an FA Cup and three League Cup triumphs - West Brom believe he has what it takes to be a manager in his own right.
"We firmly believe we have appointed the right man to keep the club moving forward," said sporting and technical director Dan Ashworth.