Novak Djokovic came from a set down to beat Andy Murray at the Barclays ATP World Tour Finals in London for his 10th win against the Scot.

World number one Djokovic defeated his US Open conqueror 4-6 6-3 7-5 in two hours and 34 minutes to remain undefeated in the round-robin tournament.

Murray won the first set 6-4 having broken Djokovic in the opening game of the match before successfully holding his serve throughout the remainder. He served out with a love service game for a one-set love lead after 44 minutes.

In the sixth game of the second set the Serbian stretched to dab a volley into the open court for his first break point of the match and the chance to lead for the first time. Murray opted to serve and volley but smacked the ball well beyond the baseline.

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• TENNIS-ATP-FINALS

  Britain's Andy Murray walks on court to play Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray walks on court to play Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Andy Murray of Great Britain walks out onto court prior to the men's singles match against Novak Djokovic of Serbia on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Novak Djokovic of Serbia walks out onto court prior to the men's singles match against Andy Murray of Great Britain on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Novak Djokovic of Serbia walks out onto court prior to the men's singles match against Andy Murray of Great Britain on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Andy Murray of Great Britain walks out onto court prior to the men's singles match against Novak Djokovic of Serbia on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray walks on court to play Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Novak Djokovic of Serbia walks out onto court prior to the men's singles match against Andy Murray of Great Britain on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Julian Finney/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray walks on court to play Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic walks on court to play Britain's Andy Murray during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic walks on court to play Britain's Andy Murray during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic walks on court to play Britain's Andy Murray during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic walks on court to play Britain's Andy Murray during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic prepares himself for his group A singles match against Britain's Andy Murray in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / CARL COURT (Photo credit should read CARL COURT/AFP/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Andy Murray of Great Britain hits a backhand during the men's singles match against Novak Djokovic of Serbia on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray returns against Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Novak Djokovic of Serbia hits a forehand during the men's singles match against Andy Murray of Great Britain on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray returns against Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray returns against Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / CARL COURT (Photo credit should read CARL COURT/AFP/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Andy Murray of Great Britain reacts during the men's singles match against Novak Djokovic of Serbia on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Andy Murray of Great Britain hits a forehand during the men's singles match against Novak Djokovic of Serbia on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• ATP World Tour Finals - Day Three

  LONDON, ENGLAND - NOVEMBER 07: Novak Djokovic of Serbia hits a forehand during the men's singles match against Andy Murray of Great Britain on day three of the ATP World Tour Finals at the at O2 Arena on November 7, 2012 in London, England. (Photo by Clive Brunskill/Getty Images)

• TENNIS-ATP-FINALS

  Britain's Andy Murray reacts after a game against Serbia's Novak Djokovic during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / CARL COURT (Photo credit should read CARL COURT/AFP/Getty Images)

• TENNIS-ATP-FINALS

  Serbia's Novak Djokovic returns against Britain's Andy Murray during their group A singles match in the round robin stage on the third day of the ATP World Tour Finals tennis tournament in London on November 7, 2012. AFP PHOTO / GLYN KIRK (Photo credit should read GLYN KIRK/AFP/Getty Images)

• Tennis - Barclays ATP World Tour Finals - Day Three - O2 Arena

  Serbia's Novak Djokovic in action against Great Britain's Andy Murray during the Barclays ATP World Tour Finals at the O2 Arena, London.

• Tennis - Barclays ATP World Tour Finals - Day Three - O2 Arena

  Great Britain's Andy Murray in action against Serbia's Novak Djokovic during the Barclays ATP World Tour Finals at the O2 Arena, London.

Djokovic also served out a love service game to take the match into a third set decider, tallying eight winners en route in his recovery.

Murray was broken again in his second service game and survived a break point later on as he continued to trail the 25-year-old Serb, but saved another break point before he broke his opponent to tie the final set at 4-4 on his serve.

Murray took a 5-4 lead but Djokovic held to stay in the match before breaking back and serving out the match for his second successive win at the O2 Arena, having defeated Jo-Wilfried Tsonga in straight sets on Monday.