The River Thames has burst its banks at points throughout Surrey, Berkshire, Oxfordshire amid warnings that even more towns along the river's waterfront could be flooded.
As rain continues to deluge parts of the UK, pictures of the swollen river surging through the counties show an alarming rise in water levels.
BBC Surrey has tweeted a picture of the Thames breaking its banks at Sunbury, part of the London commuter belt.
In Oxford some cars are underwater according to ITV news, while in Reading sandbags are being deployed to areas affected by heavy rain.
Flooding hit rail services in the Oxford area, with delays to trains between Oxford and Reading, the Press Association have reported.
The last time the River Thames broke its banks was in March 2010 when dramatic pictures showed cars submerged in Richmond.
North-west England and Wales again felt the worst of the weather on Monday night, where winds reached up to 55mph and torrential rain continued to fall on already saturated ground.
As many as 500 residents have had to be evacuated from their homes in St Asaph after the River Elwy broke its banks in north Wales.
Three people have died in the flooding and drivers and residents from across the UK face further flooding chaos, forecasters have warned.
A leisure centre has been set up to accomodate those evacuated from their homes in North Wales, while in Pickering, North Yorkshire, around 50 houses could be at risk of flooding, reported the BBC.
There are currently over 400 flood alerts and warnings in force across England.