Regular use of aspirin can more than double the risk of a leading cause of blindness in older people, research suggests.

Scientists found a significant link between taking aspirin on a regular basis and age-related macular degeneration (AMD).

The association could not be explained by a history of heart disease - the most common reason for regular aspirin use - or smoking.


AMD occurs when the middle of the retina becomes damaged, leading to the progressive blurring of central vision.

Wet, or neovascular, AMD, caused by the growth of abnormal blood vessels is the most serious form of the condition. Without treatment, wet AMD can result in a deterioration of vision within days.

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  • Different Shaped Pupils

    The pupils (the black circle in the centre of the eye) in normal people are usually symmetrical, the same size and react in the same way when exposed to sunlight. If one pupil is bigger or smaller than the other, there could be an underlying medical problem. Experts claim that differences in pupil size could indicate that the person is at a higher risk of having a stroke, brain or optic nerve tumour, or brain aneurysm. <strong>If you spot any changes to your pupils, raise this with your GP, optometrist or ophthalmologist.</strong>

  • Dry Eyes (Sensitive To The Light)

    If your eyes are always dry and ultra sensitive to light, it could signal an immune system disorder, <a href="" target="_hplink">Sjogren</a>, which impairs the glands in the eyes and mouth. The condition affects women over 40 with autoimmune disorders, such as rheumatoid arthritis or lupus. <strong>Seek advice from your GP if this sounds like you, as artificial lubricant can be prescribed and you'll be advised to drink plenty of water.</strong> "Dry eyes are more common in women over 50 due to hormonal changes," adds Larry Benjamin from <a href="" target="_hplink">The Royal College of Ophthalmologists. </a>

  • Cloudy Eyes

    If your eye is covered in a 'cloud' and your vision is impaired because of it, you may have a cataract. This causes a clouding of the lens inside the eye and can be corrected with surgery. This condition mainly occurs in older people but in younger people, it is commonly caused as a side effect of diabetes, tumours and some medication.

  • Itchy Eyes

    Although there are many things that can cause itchiness around the eyes, the most common reason could be pinpointed to an allergic reaction. The eye, and the area around it, is delicate and sensitive and more vulnerable to infections and allergies. Triggers could be anything from airborne pollens, dust or animal fur. <strong>If you suffer from red itchy eyes, try antihistamines to ease the redness, or visit your GP to organise an allergy test. </strong> If your eye and eyelids become puffy and sore, this could be a sign that you're sleep deprived. "Fluid moves around your head when you sleep and normally disperses when you wake from a good night's sleep. "However, lack of sleep causes this fluid to retain around the eye area for longer," explains Larry Benjamin from <a href="" target="_hplink">The Royal College of Ophthalmologists</a>.

  • Grey Rings

    If your eye has a light grey ring around the cornea (the coloured circle in your eye), you may have a condition called <a href="" target="_hplink">arcus senilis</a>, which is often linked to high cholesterol levels and triglycerides - fatty acids found in the blood. These are linked to higher risk of heart disease and strokes, so if you spot a grey ring circling your eye, <strong>visit your GP to discuss changing your diet. </strong>

  • Eyebrow Disappearance

    Although it's natural for eyebrows to become thinner as we age, if you notice your brows literally 'disappearing' from the outer third of the eyebrow, this could signal a thyroid dysfunction. Loss of eyebrow hair from the outer edges of your face is a common sign of hyperthyroidism (overactive thyroid) or hypothyroidism (under active thyroid). Thyroids help regulate the metabolism and thyroid hormones are vital for hair production. <strong>If in doubt, book an appointment with your GP.</strong>

  • Watery Eyes

    "Watery eyes can indicate infection," explains Larry Benjamin from <a href="" target="_hplink">The Royal College of Ophthalmologists</a>. "If the eye is watery, you've most likely got an infection caused by a virus. If it's sticky, you might have a bacterial infection." If your vision becomes blurry, this could also be the result of <a href="" target="_hplink">Computer Vision Syndrome</a> (CVS), caused by eyestrain from lack of contrast on a computer screen. This makes the eyes work harder focusing on the pixels on the screen. <strong>If in doubt, speak to your employer about booking an eye test, which is free if you use visual display units (VDU) for long periods of time. </strong>

  • Lumpy Eyelids

    Yellow lumps, also known, as xanthelasma palpebral, which appear on your eyelids could be a warning signal that your cholesterol levels are sky high. These are fatty deposits, which clump together and live in the eyelid. These are very often mistaken for a stye. Although these are quite common, <strong>it's best to get them checked by your optician or GP, as it can sometimes be an early sign of coronary artery disease. </strong> If you spot any coloured spots on your eyelids, in particular brown spots, <strong>visit your GP immediately</strong> as it could be an early sign of skin cancer. These usually appear on the lower part of the eyelid and will look a brownish colour with tiny blood vessels.

  • Bloodshot Eyes

    If your eyes are always blood-shot with broken blood vessels making them look blotchy and sore, this could be a sign that you have high blood pressure. Your optician will be able to confirm this by looking at your retina (the inner part of the eye). High blood pressure causes the blood vessel in the retina to 'kink and twist', causing them to break and look red. This could increase your risk of a stroke, so <strong>raise it with your GP as soon as possible. </strong>

  • Yellow Tint

    If the whites of your eyes have a yellow tint rather than pearly white, you may have jaundice, which is linked to various liver and gall bladder problems. A simple blood test will confirm this, so if you're in doubt, <strong>book an appointment with your GP. </strong>

The new research compared rates of wet AMD among more than 2,000 regular and non-regular users of aspirin over a period of 15 years.

Regular use was defined as taking aspirin once or more per week.

Among non-regular users, rates of wet AMD rose from 0.8% at five years to 1.6% at 10 years and 3.7% at 15 years. Corresponding rates for regular aspirin users were 1.9%, 7%, and 9.3%.

The study authors, led by Dr Gerald Liew from the University of Sydney in Australia, wrote in the journal JAMA Internal Medicine: "Currently, there is insufficient evidence to recommend changing clinical practice, except perhaps in patients with strong risk factors for neovascular AMD.. in whom it may be appropriate to raise the potentially small risk of incident neovascular AMD with long-term aspirin therapy."

Any decision on whether to stop aspirin treatment was "complex and needs to be individualised", said the researchers.

Commenting on the findings, US experts Dr Sanjay Kaul and Dr George Diamond, from Cedars-Sinai Medical Center in Los Angeles, wrote in the journal: "From a purely science-of-medicine perspective, the strength of the evidence is not sufficiently robust to be clinically directive."

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