Cancer patients can now get vital treatment in just five minutes instead of two hours after a new injection procedure was trialled by a hospital.
Patients diagnosed with follicular non-Hodgkin lymphoma (NHL), a disease that attacks one specific type of infection-fighting cell, previously had rituximab administered via an intravenous drip.
But the trial at Southampton General Hospital can now deliver a two-hour dose of drugs in around five minutes.
The procedure, which is just as effective, should now be rolled out nationwide.
Around 4,000 people, mainly in their 60s, are diagnosed with the disease in the UK every year and the majority of them will receive the drug, which targets and destroys specific proteins on the surface of cancerous cells, alongside chemotherapy to help eliminate all signs of the lymphoma and induce remission.
At the moment, most sufferers receive both treatments via a drip in a four-hour session once every three weeks.
When the six-month course of chemotherapy ends, patients often require a further two years of rituximab given over two hours once every eight weeks.
Results of the international study showed that giving the drug by a quick injection under the skin was as safe and effective as the conventional intravenous treatment.
AXA’s research found that 79% of people were able to correctly identify breast lumps as a potential indicator of cancer. But a lump or swelling in any part of the body, including the armpit, neck, abdomen, groin or chest area, is worth having checked by a doctor.
Diarrhoea or changes in bowel habits are most likely to be caused by a stomach bug or eating something that disagrees with you. But if you’re noticing changes that have lasted more than a few days, for example if your bowel movements are looser for three weeks or more, or you notice any blood when you’ve been to the toilet, then make an appointment to get it checked out.
A lot of people get mouth ulcers when their immune system is low or they’re stressed. Generally they’re nothing to worry about and, as the lining of the mouth regenerates itself every couple of weeks, shouldn’t last long. But any ulcer that hasn’t healed after three weeks merits attention from your doctor or dentist. The same goes for any sore or spot that lasts for several weeks without healing – get it checked by a doctor.
Many men find it more difficult to pass urine as they get older, needing to go more often or urgently or being unable to go when they need to. These problems are usually caused by an enlarged prostate, which is a common condition that is not in itself cause for concern. But occasionally these symptoms can be a sign of prostate cancer – either way, men experiencing these symptoms should see their GP. Similarly, while urinary tract infections are the most likely cause of women having pain or difficulty passing urine, this should pass relatively quickly. If it doesn’t, then any sudden urges to pass urine or the need to go more often should be discussed with your doctor.
It’s natural for most people’s weight to fluctuate over time. But if you haven’t instigated any changes in your diet or exercise regime and have obviously lost weight, then talk to your doctor. And if you’re experiencing heavy night sweats you should seek medical advice – these don’t always have a sinister cause, and can be brought about by certain infections or medications, but they’re worth checking.
If you’ve coughed up any blood, you should see your doctor, regardless of the amount of blood or frequency. It can be a sign of lung cancer, so needs to be checked out.
Most of us will experience coughs or croaky voices at some point, normally when we’ve had a cold. But as with many other changes to your body, anything that hasn’t gone away after three weeks or so should be investigated.
AXA’s research found women were more likely than men to identify key cancer warning signs, including breast lumps, changes in bowel habits and irregular moles. But for both men and women, ensuring you’re aware of symptoms to keep an eye out for is important. Knowledge is power: understanding what you’re looking for means you can any changes checked out quickly.
AXA’s research found only 6% of men and 3% of women check their bodies daily for anything unusual. But understanding what’s normal for your own body is essential if you’re to spot when anything has changed. If you do notice changes that are persisting for a long time, or causing you pain and discomfort, then see your GP.
A sizeable 61% of people AXA spoke to admitted they’d delayed seeing their doctor when they spotted changes that could be potential flags for cancer. But early detection of any problems can make a huge difference if any treatment is then needed. Similarly, if changes are harmless your doctor will be able to reassure you. Overall, the sooner you go to see your GP, the better.
Dr Andrew Davies, a consultant in medical oncology at the hospital who led the study, said: "This is a new formulation of a drug we are very familiar with and have been using for many years and the study demonstrates injection is equivalent to the intravenous drip method.
"In the near future, patients will be able to benefit from shorter, more convenient and potentially less complicated hospital visits, which will greatly reduce administration time for NHL patients and ease the capacity burden in busy chemotherapy day units."
Dr Davies added: "There is a high degree of patient preference and satisfaction with this new formulation of rituximab in Southampton and we hope to see it rolled out nationwide very soon."