DC Thomson, the Dundee-based publishers of the celebrated title, have released a sneak peek at the footballer's comic strip encounter with his former boss, before the issue goes on sale on Wednesday.
In 'Dennis the Menace and Gnasher and David Beckham!', Beckham decides to move to Beanotown. An undercover Dennis the Menace helps him find a home. The only problem being that it is beside Sir Alex Ferguson's new house.
Beckham played for a decade under Ferguson during his time at Manchester United.
The Beano editor-in-chief Mike Stirling said: "David Beckham features quite a lot in the anniversary issue and I think that the strip with David Beckham and Sir Alex Ferguson is brilliant.
"Dennis is up to his usual menacing and the results are hilarious. It pokes fun at their history in a lighthearted way and, of course, it's all meant in jest.
"We listen to what our readers say and feature people that they want to read about. I think that the anniversary issue is possibly the most celeb-packed issue we have ever produced."