A British Airways jet headed for London veered off the runway and crashed into a building shortly before take-off at Johannesburg's OR Tambo airport.
The plane's right wing slammed into the building as it prepared for take off. BA said 182 passengers have been taken to a hotel to spend the night.
Four have very minor injuries, AFP reported.
Oxfam's head of media tweeted a picture of the plane:
British Airways said in a statement: "A British Airways Boeing 747 was damaged while taxiing at Johannesburg airport.
"The 182 customers disembarked safely and there were no reported injuries on board the aircraft.
"Customers were looked after by our staff and provided with hotel accommodation and we are arranging alternative flights for them.
"We have launched a full investigation into the incident and are giving our assistance to the independent South African Civil Aviation Authority (SACAA) with the matter."