Price joined her 'Loose Women' colleagues - Nadia Sawalha, Jane Moore and Andrea Mclean - as they plucked off their false eyelashes and used wipes to go bare faced on Friday 19 February.
A move Mclean admitted made her feel "quite uncomfortable".
"We're the only all women show on telly," said Sawalha. "We talk a lot about the pressures we all have to look beautiful and perfect, and I think we owe it to the audience to show we don't look like this."
The segment focused on an Instagram post Cotton had shared the previous day with the hashtag #CelebrateTheImperfect.
"Ok let's reverse this scene," Cotton captioned the image. "Who is with me?
"Our social media culture is getting way out of control with filters/editing/perfect snap shots which are leading to acute pin pointing of so called imperfections.
"I want to celebrate my imperfections and embrace it all.
"So here I am. No make up, greasy hair, tired mum eye bags, bottom brace, un-plucked brows, and happy."
Moore wasn't convinced that Cotton's message was a positive as she'd intended it to be.
"I think there's something a bit militant about this no makeup thing," Moore said.
Mclean added: "Makeup-free selfies can be almost as aggressive a thing as people who post pictures of themselves at at the gym."
But Price wasn't going to take this selfie bashing lying down, interjecting: "That's me, that's what I do."
And we wouldn't have it any other way, keep the selfies coming Price.