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We Need to Hear the Whole Truth About Animal Research

Posted: 07/06/2012 00:00

Michelle Thew recently wrote a piece for The Huffington Post on the use of stray or feral animals in medical research labs. Unfortunately, the article was missing vital information that may change the way that readers understand the issue.

Ms Thew was referring to a Home Office consultation response document relating to EU Directive 2010/63/EU, which is set to raise animal welfare standards across Europe.

Ms Thew's thesis was this - the Directive would also mean that stray animals such as lost pets could be caught, with no attempt to return them to their owners, before being poisoned, electrocuted or forced to swim in laboratories.

Whilst it is true that stray animals could be used in research, in the field or in the lab, this is not the whole truth. The document actually reads:

"Article 11 prohibits the use of stray and feral animals of domestic species except in essential studies relating to the health and welfare of the animals, or serious threats to the environment or to human or animal health. There must also be a scientific justification that the purpose of the procedure can be achieved only by the use of a stray or a feral animal."
Page 17, Consultation on options for transposition of European Directive 2010/63/EU on the protection of animals used for scientific Purposes. Summary report and Government response, May 2012.

The use of stray or feral cats would, then, be either to treat diseases in that species, or the very highly unlikely situation of a 'serious' threat to humans, animals or the environment that could only possibly be studied in stray animals. It would otherwise be illegal.

It is not possible to know what the nature of the threat could be, so the government has not ruled anything out. However, animals like humans are vulnerable to outbreaks of diseases such as rabies, or environmental changes that have a profound effect on their chances of survival. In the case of a disease, the 'use' could be the testing of a vaccine, perhaps by pill or injection rather than the gratuitous electrocution of a beloved family pet. It might equally be the study of feline HIV in feral cat populations, which is unlikely to involve taking them for a swim.

Researchers proposing a vaccine or treatment would have to prove that testing the vaccine on a stray or feral cat, rather than via another technique or animal (including laboratory-bred cats), was literally the only way to proceed, in order to get a licence from the Home Office that allowed them to do the work. They cannot simply grab animals off the street. In doing this research, they would be attempting to protect Europe's cat population from the spread of a deadly disease.

Animal welfare groups such as the BUAV often do good work, rightfully exposing breaches of the law and helping to refine policy around, for instance, conflicts of interest. Unfortunately, some of them have also convinced themselves there are alternatives to animal research, when this viewpoint is both scientifically bogus and a self-defeating argument: It is already illegal to use animals if there is a proven alternative. Although work continues apace to find alternatives and reduce the numbers of animals used, we are not there yet. If there are genuinely alternatives, available now, all protesters have to do is produce them and a grateful scientific community will be legally compelled to use them.

The article also exposes other examples of rhetorical tricks that anti-vivisection groups can use to make their case. These include neglecting to mention the key safeguards of the legislation, exaggerating the probability of stray animals ever being used, examining only the costs of animal research rather than the net benefits to animal welfare, building a 'straw man' argument using the definition of 'severe procedures', concealing government safeguards outside of the legislation, listing experimental techniques that are highly unlikely to be used, divorcing research techniques from the purpose of the procedure and making a false claim to moral authority when animal research is key to both human and animal welfare.

There is also a tendency for anti-vivisection lobbyists to resort to emotive language when describing research, which can be easy to do when describing any medical procedure. Even a visit to the dentist can be made to sound pretty hair-raising if you use enough colourful allusions and ghoulish imagery. If you then omit the reason you were there in the first place it begins to sound like an outrageous assault, rather than an entirely necessary procedure.

It is absurd to claim that the researchers who create the drugs found at the vet's clinic are opposed to animal welfare. They may instead be making a decision to sacrifice one animal's welfare for that of many, but this, surely, saves more animals from suffering and premature death.

In contrast, anti-vivisection lobbyists champion not animal welfare but "an" animal's welfare, advocating the rights and welfare of individual animals, but not the majority of animals or animals as a whole. To call it "Animal Libertarianism" is taking it a bit far, but it is a type of 19th century individualism which has found itself advocating individual welfare over the welfare of the community or wider species. As with every set of rights, there is a conflict at some point between the rights of the individual and the welfare of others. By wholly backing the individual, they find themselves ignoring the greater needs of a larger population.

Animal research is a tough topic to discuss, a task made harder by breathless but groundless anti-vivisection narratives that mislead the public over various aspects of the issue. Whilst not doubting that anti-vivisection organisations are well-intentioned, it is time for them to consider how, if their beliefs regarding alternatives happen to be misconceived, this affects their moral position.

In an echo of Mark Henderson's Geek Manifesto, we too call for the public, and particularly scientists, to write to their MPs, asking them to stand up for human and animal welfare by supporting the scientific community and animal research, and at very least reassess some of the claims and concerns of lobbyists like Michelle Thew in the light of their tendency to mislead.

Click here to write to your MP today.

 

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06:25 PM on 06/27/2012
forgetting the home office for now, why have we got Understanding animals research (UAR) There always seem to be using quotes that make out as if cures are "about" to be found, should not they teach us un-educated humans the whole facts?, are they saying that no body as in (humans) suffer because of animal testing? EVER, why have we a cure for cancer in a mouse but cannot say the same about cures for humans?, cancer is not a new disease, who is supporting (UAR) in other words who is paying your wages is it giant pharmaceuticals? i also noticed an opinion poll below, which said 85% of public support Animal research, but then researched, it was ran by the research companies and the questions could not be answered to show any other result, can someone please answer these questions i have, i watched a video and a debate the other day and want to know why it is so hard to understand some facts, and i cant find the answer, thanks look forward to understand more,
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Chris Magee
03:10 PM on 07/17/2012
Hi Alan,

This is our membership and funding list http://www.understandinganimalresearch.org.uk/about-us/membership-and-funding. It reflects the facts that only 26% of procedures are undertaken by commercial organisations, while the rest is undertaken by non-profit organisations, public bodies, public health labs, hospitals, charities, universities and medical schools.

I suppose one difficulty we have is explaining just how much research goes into producing treatments. For each drug that makes it to market, for instance, between 5,000 and 10,000 turn out to be dangerous or ineffective. All of these candidate drugs would have been hypothetically effective cures.

In terms of curing mouse cancer - don’t forget we’ve been making advances in human cancers too. All that it means is that not everything that works in mice works in humans, but the ones that do have been worth having. Try this video for more information on that point http://www.youtube.com/watch?v=n0OTU5fc-K8&feature=youtu.be

It should be remembered at this point that developing treatments and understanding biology through animal research is for the benefit of animals humans alike. Creating a vaccine for feline HIV, for instance, would have involved testing that vaccine on cats, probably via injection – which is also animal research. This is partly why 95% of procedures are classed as mild or moderate – the pain threshold for what a “procedure” is very low.
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HUFFPOST BLOGGER
Chris Magee
03:10 PM on 07/17/2012
It’s unfortunate that computer models cannot be used as a replacement, but you cannot model what you don’t yet understand. We are getting there with alternatives – Google NC3Rs for the latest progress on that. – but we’re a way off yet and so are focussing on minimising the number of animals used and switching to lower life forms like fruit flies instead of mice where possible. It’s worth noting there were big drops this year – 47% fewer new-world monkeys, 21% fewer dogs.

Also, many people do not seem to realise that researchers already use the “alternative” methods such as computers and cell cultures, often as part of a study that also uses animals. Computers can’t even model a healthy organ at the moment, let alone a whole body or a diseased whole body. We’re also not sure of how biology functions at the micro level – if we did we wouldn’t need to do the experiment.

As for your polling point, each year the government commissions MORI to test public opinion, and generally speaking people are supportive of animal research if there’s no other way to cure disease and unnecessary suffering is carefully avoided – this is called “conditional acceptance”. See page 14 of this document http://www.ipsos-mori.com/Assets/Docs/SRI_HEALTH_BIS_NC3Rs_combined_animal_experimentation_2011_FINAL_report_PUBLIC_110411.pdf for evidence, although as you can see it’s a dynamic figure and can fluctuate up and down year-to-year.
07:05 PM on 07/17/2012
researchers wanting to find the reason why older people cannot sleep, then test animals to understand their clock cycles ?, home office papers, and yes they may be not an "alternative" available, but surely that does not mean use something else thats left to get us by, many patients die with adversity to the same tested drugs, i would be worried about one person dying not 20'000 every year, my personal thoughts on UAR, you are doing yourself no favours in letting speaking of research to the talking, they come across like an extremist mob, i also disagree with pro animals research making out that the history of cures was down to animals, it comes across to the public quite comical and dis trusting. and talking public opinion, "if no cruelty involved", home office cruelty reported cases 2011, research personal licences mis use of, mice left to starve by accident and lazy ness , guinea pig drowning from a burst pipe, research done with out consent, GSK not been honest to FDA, fines of 3 Bill dollars, tax avoidance in the UK, Roche etc the dishonesty, how can we trust the very people you promote , name a breakthrough please for 2012 not a "might be" or "could be", or a new kind of house cleaner or cheaper similar pill, but a new cure for the benefit of human beings, and who funds and makes the questions on the MORI test, thank you,
12:30 PM on 06/21/2012
Scientists don't have to 'prove' anything to the Home Office, claims in licence applications are generally accepted at face value as Inspectors have neither the time nor the inclination to challenge assertions regarding potential costs and benefits. This is inadequate because, in the cases I've seen, applicants normally underestimate animal suffering and exaggerate potential benefits. It is basically a rubber-stamping exercise. The Minister has recently admitted to Parliament that not a single licence application has been refused by the Home Office between 2008-2010 - that's 9908 out of 9908 approved. The legal/democratic problem here is that researchers/inspectors operate a very different cost-benefit criteria compared to the public's view and the impression given by researchers/Home Office. For example, approving substantial severity procedures on wild-caught baboons for the purpose of advancing knowledge (i.e. not justifying in terms of any practical medical benefit - see the previous Chief Inspector's report into the Imutran xenotransplantation research, published in 2001).

It's interesting that UAR constantly claim that we have a strict regulatory system (if only!), while behind the scenes lobbying for precisely the opposite, e.g. for Inspectors to have a merely 'advisory' rather than regulatory role.
01:45 PM on 06/26/2012
Hang on a minute – this is a question about policing. Because some people break the speed limit doesn’t mean the speed limit is wrong!
02:22 PM on 06/26/2012
What is a question about policing, and what are you comparing to a speed limit?
12:43 PM on 06/29/2012
So, seems like 'biggerjim' is a bit of a troll? A very corporate, hit-and-run approach to debate. Happy to make vague assertions but reluctant to have detailed discussion.
11:22 AM on 06/27/2012
That approval rate doesn't include all the licences that in the end were not submitted - because of the role of the Home Office Inspector it is virtually impossible that any application will be made that will not be approved. Any such proposal is weeded out by internal ethical committees or in consultation with their Inspector - or extra welfare safeguards are put in place to lessen any suffering involved with the testing.

That's the trouble with statistics that only cover the final stage of a (sometimes) quite lengthy process seeking approval.

The current system is certainly not a rubber stamp!
12:19 PM on 06/27/2012
In terms of Inspector time, the process is not lengthy - just 1.5 days per project licence which is woefully inadequate given the size and complexity of the average project, the cost-benefit assessment, checking for application of 3Rs etc. So the claim that they routinely spend a lot of time on pre-application advice isn't plausible. Interestingly, the HO also don't bother to monitor Inspectorate time spent on pre-application advice despite the critical role they say it plays (they do record time spent on formal applications). Even if the pre-application process did have some impact, 9908 applications approved out of 9908 is still bizarre.

The only Home Office figure I've seen is for 2010, stating that Inspectors offered pre-application advice on 44 preliminary applications that weren't proceeded with. But, significantly the HO doesn't say they weren't proceeded with because of Inspectorate advice. There could be a whole range of other reasons. Oddly, the 44 figure is provided in an Inspectorate report, yet the Minister has told parliament they don't record these instances and refuses to provide meaningful info about the process.

I daresay some Inspectors and institutions are a little more rigorous than others, but overall the bar for getting a licence approved is very low because noone in the system really has the time or inclination to challenge applicants' assertions. But if you know of cases that challenge that interpretation then I'd be interested to look at them.
09:44 AM on 06/11/2012
why aren't you calling for greater transparency from animal testers and the government? Doesn't this secrecy add to people's concerns over animal testing by indicating there's something to hide. Nobody believes the spurious argument that it's to protect researchers from animal rights extremists - the public doesn't want names and addresses, it wants stats and science made open. Credit the public with the ability to form its own judgement on the use of animals in labs, unless of course the figures would cause justifiable outcry. Chris Magee is wrong in trying to justify this abhorent proposal, one wonders how he'd stop it becoming an industry - only hope people react with outrage and show the government its disgust. Mr Magee clearly never owned a dog.
01:36 PM on 06/11/2012
The stats and science you are looking for is on the Home Office website. There is an Excel sheet showing how many animals of what sort are used for what purpose. There are commercial reasons some stuff can not be open, just like Apple is secretive about the next iPhone, and you can say no one believes researchers are attacked, but the police will disagree with you.

In other eu countries they don't have such attacks and the labs are open in the way you describe.
08:43 PM on 06/08/2012
Michelle Thew discussed the issue of stray pets being used in research experiments which is a real possibility, although it would only occur in very rare circumstances in the UK. However, this is not the case in other areas of the world, including the United States, where former pets are regularly used in experiments.

Michelle also addressed many other important issues including concerns associated with the secrecy that surrounds animal experiments and the fact that researchers can hide information about animal experiments from Freedom of Information requests. It would have been very interesting to also hear Chris Magee’s thoughts on these issues, which are of great concern to both anti-vivisection groups and the general public, rather than just hearing his views on the use of stray pets.
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Paul Wagland
Resistance is fertile
09:18 PM on 06/07/2012
Personally I don't object to animal testing if it has a good chance of contributing to the eventual cure for a serious illness (either in humans or animals). The 'needs of the many' argument is pretty straightforward. However I don't understand why this applies to animals and not humans. Why don't we run trials of cancer treatments on people with terminal cancer? Or (moral minefield alert) convicted killers? I'd bet you wouldn't be short of volunteers, at least of the first group.

More directly relevant to this article - under precisely what conditions would it be necessary to test on a stray domestic animal, rather than a lab-reared one? Surely that would only matter to someone studying psychological conditions? Hardly life-saving. It's more wrong perhaps to test on a creature that has known freedom, love etc than it is to test on one that has been reared in a lab for the purpose.
01:31 PM on 06/21/2012
Thing is - nine out of ten potential new drugs that look promising in animal trials simply don't work when they're given to humans. Or worse still, they cause serious side effects. Animal testing is not the best way forward and certainly isn't the only way, in spite of what some researchers tell you.

The original article accused anti-vivisectionists of misleading the public but so do some researchers. We certainly DO need to hear the whole truth about animal research, not just one side of the discussion.
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Thismortalcoil
Science is the poetry of reality
02:36 PM on 06/07/2012
All this noble-sounding talk of progress and the greater good masks the fact that much of this research is simply carried out to make profits for the drug companies. Countless lives are wasted testing replica drugs to ones already available.

Killing in the name of looking for cures for illnesses that we already know how to prevent is morally questionable, and more should be invested in public information to help people to take responsibility for their own health.

Prevention is better than cure and a huge number of human and animal deaths could easily be prevented if people simply made the effort to ensure a proper diet and exercise for themselves and their pets.

I'm sure that some animal research is justified, but claiming that it is 'key' to human and animal welfare, and claiming that it is supported by the whole scientific community is hardly 'the whole truth.'
03:04 PM on 06/07/2012
No - 48% by academia, 17% by drug companies. Your conspiracy theory is invalid. Other than that you think it's not OK to cure anything preventable - which is your opinion, fine. We happen to disagree as sometimes people don't have a choice but to breath fumes. support by the scientific community = Magee works for Understanding Animal Research and here's their membership list http://www.understandinganimalresearch.org.uk/about-us/membership-and-funding
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HUFFPOST SUPER USER
Thismortalcoil
Science is the poetry of reality
03:26 PM on 06/07/2012
Firstly I didn't say it's not OK to cure anything preventable, I said it's morally questionable, so the pros and cons of each case need to be weighed up carefully. And the example you cite, where 'people don't have a choice but to breath fumes' isn't a great example of 'preventable' is it?

Secondly, are you actually claiming that no research is carried out purely for the profit of drug companies?
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HUFFPOST SUPER USER
Paul Wagland
Resistance is fertile
09:20 PM on 06/07/2012
So where is the other 35% carried out? What's your source for that claim?
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HUFFPOST SUPER USER
Thomas Platt
04:26 PM on 06/07/2012
So if everyone were healthy then no-one would ever get sick? That's a little naive - personal responsiblity is an important step in prevention of illness, but things like cancer exist independent of cigarettes and trans fats. Heart disease happens to even very fit people. You can never smoke a day in your life and get lung cancer.

Is it better to eliminate those things that can aggravate and cause those diseases? Of course, but that still leaves an incredible number of diseases and disorders without explicit societal causes that still need to be addressed.
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HUFFPOST SUPER USER
Thismortalcoil
Science is the poetry of reality
04:36 PM on 06/07/2012
Thomas, you're the one being naive - personal responsibility isn't just 'an important step' it's the single most important thing you can do to prevent illness.

We're living in a society where obesity is an epidemic and very little is being done to educate the public and help prevent perfectly avoidable deaths.
This comment has been removed.
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HUFFPOST SUPER USER
Ben Wilson
What's the story mourning Tories?
02:22 PM on 06/07/2012
The animals right groups seldom have the public on side, and the big egos of these groups do much to convince themselves otherwise. We don't want animals being abused, and many will take excepetion to animal testing in the cosmetics industry, but we credit scientists with having good reasons to test on animals. We're all for alternatives, but not for waiting for to emerge, it's up to the critics to eliminate the need for animal testing, not the people who believe it to be a sound method of research.

And just to point something out. There are endless medical trials always taking place. We do test things on ourselves too, not just the liccle bunny rabbit.
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HUFFPOST SUPER USER
Thomas Platt
04:14 PM on 06/07/2012
I would disagree with your assertion that animal rights groups seldom have the public on side. My take on it is that most people don't care strongly either way about animal research, but those that do are vehemently anti-animal testing.
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HUFFPOST SUPER USER
Ben Wilson
What's the story mourning Tories?
07:47 PM on 06/07/2012
Yes, I agree with how you put it.
05:42 PM on 06/07/2012
That's true. Detailed and robust opinion polls carried out over the past decades have shown high levels of support for the use of animals in research when certain conditions - which essentially equate to the UK regulatory system - are met. The latest Ipsos-Mori poll put public support for animal research at over 85% http://www.ipsos-mori.com/DownloadPublication/1343_sri-views-on-animal-experimentation-2010.pdf

That said the same polls also showed that the public did not appreciate just exactly how tightly animal research is regulated in the UK...so lets have more articles like this one from Understanding Animal Research to set things straight please!
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Ben Wilson
What's the story mourning Tories?
07:58 PM on 06/07/2012
That last point is the major one I think. People really dont appreciate how heavily regulated animal testing is in the UK.
11:23 AM on 06/07/2012
Finally – someone standing up for common sense. Why do “animal rights” activists think that it’s better that entire populations of animals die painfully rather than a few receiving a harmless injection in the lab. That’s not animal rights. That’s like seeing a house on fire with one cat in it, and Battersea cats Home on fire and deciding to send the fire brigade to the house.
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Paul Wagland
Resistance is fertile
09:02 PM on 06/07/2012
Did 'entire populations of animals die painfully' before we had animal testing to save them?
06:44 PM on 06/11/2012
Animals get diseases and illnesses, just like people. So yes. Research being done with dogs, for instance, directly benefits other dogs AND humans. humans and dogs get a lot of the same kinds of cancers, diabetes, and neurodegenerative disorders like Parkinson's and Alzheimer's. So whatever treatment they're coming up with for bone cancer can work on humans AND dogs!
07:29 PM on 07/17/2012
"rather then a few receiving a harmless injections' have you every been in these labs where 3.7 million animals are, my version of a quote, wonder why we dont take our children to the vets, and our dogs to a doctor, my guess is the child would be better off,
11:16 AM on 06/07/2012
Perhaps the prevailing motivation (and legal obligation) of maximizing "financial/currency profit" (rather than optimizing the "real profit") distorts the incentives, ambitions and perceptions of well intentioned, good, scientists. This is undoubtedly true of their managers.
The rate of progress is maximized (without much regard for its (that is the rate's) necessity or consideration of the costs than are not monetarily or immediately quantifiable. (and of course, if the costs are not at the research investors' expense, they are definitely not in the equation.)
The human (or feral) cats specie's existence is not endangered. There is no need for the present mad rush for "progress".
The (anti) monopolies, cartel, competition authorities have allowed too much conglomeration (and thus concentration of power) of pharmaceutical (etc) companies.
Never forget that most research is not for the general welfare of all or most. It is for the welfare of those who already do not require more welfare.
The bottom line (to use an accounting term) is that while the distribution of resources continues to be further skewed towards the wealthy, this means that there is not real progress.
When real education (not the provision of fairy tales) has reached the level that every (laboratory, slaughterhouse, military, medical) worker would be willing to show all their children EVERYTHING they do at work, then we have significant progress.
In case you get the wrong impression, I am very very pro science.
11:28 AM on 06/07/2012
I think any epidemiologist would thoroughly disagree with you. Outbreaks are a question of when and what, not if. Saying we shouldn’t allow research into a disease in the future because it’s not prevalent now is suicide. And of course it’s for the benefit of majority. 150 cats are used in medical research each year, most for veterinary research – and they benefit the other 7,200,000 cats in the UK. As I understand it, you’re an accountant who doesn’t know which is larger out of 150 and 7.2 million.
07:12 PM on 06/07/2012
I can't stand cats.
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Paul Wagland
Resistance is fertile
09:32 PM on 06/07/2012
I've read that 3.54million animals died in scientific tests in 2010. Those are Home Office figures I think. Many more are bred but destroyed (unsuitable or surplus to requirements).

150 cats is hardly representative.
09:32 AM on 06/07/2012
Ah, the greater good, a lost ideal of the modern age where each individual is greater than the society as a whole. I love animals as much as the next person but can also see that the sacrifice of one for the good of the many is sometimes the only way to make progress. As long as those making that progress are responsible who am I to argue.
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Paul Wagland
Resistance is fertile
08:59 PM on 06/07/2012
So would you volunteer yourself to be infected with HIV so scientists can study the outcome? In the interest of humanity as a whole I mean?
01:33 PM on 06/21/2012
Lots of people who are already infected might just offer to be a test subject - if they were asked.
08:43 AM on 06/07/2012
Why is there a distinction between family pets and feral animals when discussing animal experimentation?

It's like saying child abuse is not ok, unless the child is neglected.

Or that we can do physically painful studies on people, but only if they are homeless?

Animal abuse is animal abuse.

This "scientific method" has no place in 2012.
09:58 AM on 06/07/2012
Points 1-3 There's no distinction. That's inherent to the wording of the legislation. Read it again.
Point 4 - It's an injection. Would you accuse a vet of animal abuse?
Point 5 - Unless you want to cure animal diseases and stuff
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ginadeoliveira2008
Seen a shooting star tonight and I thought of you
08:57 PM on 06/06/2012
I'm absolutely unable to read that. The tittle alone gives me creeps. I think of the feral cats I feed and shelter whem they appear in my yard. I think of my indoor cats. I feel for those poor things.