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In Reply - Can Cannabis Drive You Crazy?

Posted: 08/02/2012 15:31

I'm not a fan of rebuttals, they can often be interpreted as rude or standoffish. This is certainly not the flavour of my reply, and so with this ample disclaimer in place, I would like to politely address Mr Rupert Wolfe-Murray's first HuffPo blog; Can Cannabis Drive You Crazy?

As ever, when cannabis becomes a contested issue, it provokes reaction. Why is such an emotive investment given to a plant, and why do we still have an insipid discussion over this drug? Well, the first clue is in Mr Wolfe-Murray's first paragraph:

"...cannabis can help the elderly and infirm dull their pain"

Although the original prose is not about therapeutic benefits of cannabis, Rupert's opener does give some insight as to why such passion orbits the subject. Cannabis has many recognised and peer reviewed benefits, and to an individual who's locked in a battle with ill health, cannabis does provide a unique lifeline and harm minimisation in comparison to pharmaceuticals. So when a substance becomes a generic black and white issue that focuses on the negatives, and it's for everyone to be swept along with the same risible broom - the result is a backlash from those who are impassioned. As understandable as this is, it doesn't often prove useful. Current law and dialogue exsist to deter children from using, but the result is that all consensual adults still face up to 14 years in prison.

Mr Wolfe-Murray goes on to ask:

But can someone please explain the logic of decriminalising the possession of a substance which is illegal to supply? If I'm allowed to smoke dope does that mean the law turns a blind eye when I do a transaction with my supplier?

The logic is simple, and it's one that the Home Office acknowledges. When addressing the legal high market, the government did not choose to criminalise those in possession once the ban came into play. It was said that the criminalisation of the young has no societal benefits - this is owing to the lack of prospects due to a criminal record. Emphasis was placed on chasing supply routes. This, in essence, is how Portugal handle their drug policy.

Mr Rupert Wolfe-Murray then says,

When I was a student I thought cannabis was a harmless pastime, no worse than alcohol, and I was encouraged by the fact that it's not addictive.

Many years later I ended up working for an addiction rehab clinic in Scotland where I found out that not only is cannabis addictive but the skunk version of the drug is known to send as many as 20% of users into a psychotic state. In other words, it can drive you mad. And everyone knows that the THC content of street cannabis has been going up for years.

Pretty much any scientist would of course agree with Rupert's statement that cannabis is less harmful than alcohol: The Lancet published a harm scale of drugs and is widely regarded as accurate. The Department of Health also conveys an accurate source of information and drug related harms; the publication: A Summary of the Health Harms of Drugs is aimed at healthcare professionals; there's a notable disparity between the messages of harms that we've come to know in the UK to what is actually scientifically proven. Does this impact the drug education of our young? When reality doesn't measure up to the projected, virulent harms -- does this give way to a distrusting and confused youth?

Rupert Wolfe Murray continued:

I wonder if Sir Richard and his chums on the Global Commission on Drug Policy have been fully informed of the risks involved.

They should talk to Sue Philips from Newcastle as she was addicted to almost every drug available, as well as the methadone peddled by the NHS, for over 30 years.

Putting a pin in the example of a lady that admits she's been addicted to most drugs, it soon becomes apparent that Mr Wolfe-Murray hasn't read the Global Commission Report, or even indulged in a summary of the paper. It is owing to the potential and possible risks of any drug that the Global Commission makes its recommendations of a regulated market. At no point in the Global Commission report does it allude to any drug being safe, harmless, fun. Like most reform groups, it has seen the alarming trend in related harms owing to the feral nature of current drug controls, and addresses the complexity of the problem. This is perhaps the most irksome point of drug policy: the stringent belief that those wishing for reform do so based on nothing other than how 'safe' and beneficial a drug is when the antipode is true.

Of course, children should be prevented from using any substance, that's a given, but current law is compounding the culture of illicit substance use. A regulated market will not eliminate underage drug use, but it will certainly curtail and restrict.

As someone who works in an addiction field, Mr Wolfe-Murray must be aware how unattractive it is for those wishing to seek help with substance abuse owing to the punitive nature of law. Invariably, only those that can afford the privilege of rehab are the ones that can beat addiction. The example of a lady who has been addicted to most drugs is a clear indication that the notion of addiction & abuse is the problem, and not generic perceptions of individual substances. By all means, harms of all drugs need addressing, but current law does not allow this in a 'just say no' culture. Living in a constant state of altered consciousness is of course going to be crucially affecting, but the lack of citations in Mr Wolfe-Murray's blog becomes lucidly apparent at the mention of cannabis psychosis -- working in a treatment environment, you will get to see more cases of addiction and psychosis than the average person, but there's a statistic that Mr Wolfe-Murray uses that many have been left wanting a source. He says,

I found out that not only is cannabis addictive but the skunk version of the drug is known to send as many as 20% of users into a psychotic state. In other words, it can drive you mad.

The 'it can drive you mad' statement is a gross misinterpretation to say the least, no scientist will put their name to such a overstated claim. The ACMD undertook one of the most comprehensive reviews of cannabis to date. The conclusion? To stop 1 case of cannabis psychosis, you'd need to stop 5000 young men from using, and 7000 young women. And if that's not enough, I often use Dr Ben Goldacre of Bad Science at this juncture, and I should do so once again, he is indeed hard to argue with. By anyone's measure, the risks of psychosis are incredibly slim.

And to finally address 'skunk?' - I have done so at length.

So in answer to Mr Wolfe-Murray: cannabis does not drive you mad, and it is dangerously hyperbolic to suggest so. Drug policy is trying to move away from sensationalism and onto an evidence based platform where we can address harms and give rise to emplacements that will sufficiently decrease them. A regulated market of cannabis will give a correct balance of cannabinoids over the dire quality 'street weed' and 'soapbar' that now makes up most of the UK market. Regulation will give proper titration advice so as to avoid inadvertent abuse, and will stem the flow of teenage usage.

Or, we can continue down our current path and see more of the same.

 

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I'm not a fan of rebuttals, they can often be interpreted as rude or standoffish. This is certainly not the flavour of my reply, and so with this ample disclaimer in place, I would like to politely a...
I'm not a fan of rebuttals, they can often be interpreted as rude or standoffish. This is certainly not the flavour of my reply, and so with this ample disclaimer in place, I would like to politely a...
 
 
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01:36 PM on 02/18/2012
I was a drug addict too! But now i have a new life, thanks to some tips that me and my friend realised everyone can do to start a new life and let the weed and other stuff behind. Just follow http://quitmarijuana.nightwin.com and get a new life!
07:51 PM on 02/12/2012
I typed a long reply to montana Biotech but my reply strangely vanished!

The sad part is that this spray is the only way MS sufferers in the UK will get cannabis to relieve their spasms without breaking our draconian laws.

Gone though are the days when they could claim that it has NO medicinal benefit, that has to be a good thing.
04:27 PM on 02/16/2012
Just trying to point out that big pharma is sitting back and waiting to CASH IN!

!!BREAKTHROUGH!! Hermaphrodite test for your cannabis plants! http://wp.me/pJR5Y-16B I have been working in the lab on this for a while! It works, finally. I hope others who cultivate can see the utility.
07:39 PM on 02/16/2012
Yeh i got that,it is not how i would a decent society should behave but then show mw a decent society and i'll show you a liar. Happily the rest of us can carry on as normal eh, nothing much has changed in all these years.
03:17 PM on 02/12/2012
You have heard of Sativex by GW Pharmaceuticals, yes? Now find out that Bayer AG is a partner with them! http://www.gwpharm.com/gw-partners.aspx Bayer, who are they? http://en.wikipedia.org/wiki/Bayer

Now you know why this administration has been so admit about stopping medical cannabis. They are paving the way for the BIG guys!
HUFFPOST SUPER USER
Tony Booth
01:27 PM on 02/12/2012
thanks for all that work jason, i'm getting heartily hacked off trying to correct the misconceptions generated by a press that is heavily influenced by the alcohol and pharmaceutical industries.
you've saved the rest of us alot of writing, thanks.
12:33 AM on 02/12/2012
Good news for MS sufferers, GW Pharmaceuticles launched a fully tested cannabis mouth spray -

http://www.gwpharm.com/Sativex.aspx

Hope Huff leave my link up as this is important to millions of people worldwide.

Maybe we can have an injection of common sense in the drug debate after all.
11:16 PM on 02/11/2012
We shouldn't buy illegal drugs. It is selfish. We are paying for carnage, of which tens of thousands of tortured, gruesome deaths in Mexico is just a starter.

Make it legal, grow your own, I don't care. But please don't finance misery and death for thousands of other people purely for a little self indulgence.

The article focuses on what cannabis does to us. It is a grave error not to address the more important issue of what it does to others.
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08:15 PM on 02/09/2012
Good job cutting through the reefer madness!!! It makes you wonder who is truly mad. I really like your writing style too, it's not dumbed down yet it is still easy to read, kind of conversational.
10:45 AM on 02/09/2012
What i find amazing is that canabis causes so much paranoia and hysteria, in people who dont actually use it.
09:01 AM on 02/09/2012
Personally,I don't like skunk,it wipes me out,I can live on hash tho.Think I'll grow me own..
08:55 AM on 02/09/2012
Depends on the strength and amount probably,check the difference between the man who's had a pint of beer and the one who's had a bottle of whiskey.A lot of things are beneficial in small doses but will kill you in large ones,Aspirin for instance.The trouble with young people is they tend to think they're invincible until they get killed.Careful out there..
08:46 PM on 02/08/2012
http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4

Cannabinoids may cause antitumor effects by various mechanisms, including induction of cell death, inhibition of cell growth, and inhibition of tumor angiogenesis and metastasis.[9-11] Cannabinoids appear to kill tumor cells but do not affect their nontransformed counterparts and may even protect them from cell death. These compounds have been shown to induce apoptosis in glioma cells in culture and induce regression of glioma tumors in mice and rats. Cannabinoids protect normal glial cells of astroglial and oligodendroglial lineages from apoptosis mediated by the CB1 receptor.[12]
08:46 PM on 02/08/2012
http://grannystormcrowslist.webs.com/

i love granny!

This year‘s message to all of you is a little different. I am going to be explaining a major scientific discovery - the Omega-3/CB1 connection and how it affects your healing with cannabis! But to understand fully this discovery, we need to revisit Biology 101.

Every cell in your body has tiny chemical receptors all over the cell‘s skin or cell membrane. These receptors work kind of like an ignition switch - you put the right type of chemical key into a receptor and it turns on some kind of action. The type 1 cannabinoid receptors (CB1s) are the ones we are interested in looking at. They are found in the body and the brain.

Turning on a CB1 receptor with either an endocannabinoid that your body makes, or a phytocannabinoid like THC, can result in many different things occurring. A cancer cell may be told to die through a process called apoptosis, it may activate a basic instinct such as nursing, soothe an irritated digestive tract, or simply ease your pain. The CB1 receptors in your brain are the ones to blame, or praise, for the cannabis high.

And this is where the cutting edge of science starts - to make functional CB1 receptors, you absolutely need Omega-3 in "Nutritional Omega-3 deficiency abolishes endocannabinoid-mediated neuronal functions", the Omega 6-rich western diet is implicated in our declining mental and physical health. The ideal proportio....
08:43 PM on 02/08/2012
http://blog.norml.org/2011/10/24/5-favorite-law-enforcement-lies-about-marijuana/
the prohibitionists are coming out in full force with hysterical propaganda to once again terrorize voters about cannabis. We intended to scour multiple sources to compile the five most common scare tactics they use, but Joseph Summerill, director of the Summerill Group LLC, a Washington, D.C.- based law enforcement think tank and general counsel for the Major County Sheriffs’ Association, made our job easy by using all five in one op-ed piece published today in the Washington Examiner entitled, “Facts on medical marijuana are stubborn things, too“.

Lie #1) Marijuana’s not really medical. The government says so!

[M]arijuana is a Schedule I drug… a high potential for abuse or dependency… no accepted medical value… unsafe to use, even under medical supervision. [M]arijuana has not passed the rigid scrutiny of medicine proposed by the FDA.

The Truth

National Institutes of Drug Abuse (NIDA) puts the lifetime dependence rate on cannabis at 9%, same as caffeine. Alcohol has a 15% rate of abuse and Tobacco’s is 32%.
One third of federal jurisdictions (16 states and DC) accept the medical value of cannabis.
The federal government is supplying four Americans with this “unsafe” medicine with no medical supervision.
Cannabis has been used medically for 5,000 years without a single human death – a far greater safety standard than an FDA that approved phen-fen and Vioxx......
photo
PoetPeter
Better known as Peter Reynolds, leader of CLEAR
07:31 PM on 02/08/2012
Especially for karen1963yorks but for all others interested in the scientific evidence about cannabis and mental health.

1. Hickman et al, 2009. A review of all published research so, by definition­, not cherry picked. It shows that the risk of lifetime cannabis use correlatin­g with a single diagnosis of psychosis is at worst 0.013% and probably less than 0.003%.

2. Hospital Episode Statistics. Count of finished admission episodes (FAE) with a primary diagnosis of mental and behavioural disorders due to use of cannabinoids (ICD10 code F12) and alcohol (ICD10 code F10)

Cannabinoids (F12)

2009-10 713
2010-11 799

Alcohol (F10)

2009-10 47,402
2010-11 47,287

Source: Hospital Episode Statistics (HES), The NHS Information Centre for health and social care.

There are three million regular users of cannabis (Atha et al 2011) and 31 million regular users of alcohol (NHS Information Centre 2009). Therefore alcohol use is six times more likely to result in admission for mental and behavioural disorders.

3. Frisher et al 2009. The ACMD commissioned a study by Keele University into the trends in schizophrenia specifically to test the claims in the media of a link between it and cannabis. It looked at almost 600,000 patients and concluded that "..the incidence and prevalence of schizophrenia and psychoses were either stable or declining" despite alleged increased use of allegedly more potent cannabis.