Some have dubbed it the biggest music event in history and a look at the line-up reveals why.
Bruce Springsteen and the E Street Band will kick things off followed by Paul McCartney, the Rolling Stones, the Who, Bon Jovi, Eric Clapton, Dave Grohl, Billy Joel, Alicia Keys, Chris Martin, Eddie Vedder, Roger Waters and Kanye West.
Watch all the action live from 11:30pm GMT