A man has been shot dead at a house in what police described as a "targeted attack".
The body of a 55-year-old was found at a property in Clifton, Salford on Sunday evening.
Security has been stepped up in the area and Manchester Road remains closed.
The victim has not been formally identified, police said.
Detective Chief Superintendent Russ Jackson said: "People will understandably be alarmed when they hear about this incident which we believe was a targeted attack.
"I would like to reassure the public that we have a heightened level of police officers in the area while we establish the full circumstances of the incident and identify those responsible.
"We are actively following a number of lines of enquiry however, I would urge the local community to come forward if they saw or heard anything in the area.
"I urge anybody with any information about what's happened to come forward. I want to stress that any information received will be treated in the strictest confidence."