The Government will impose a new contract on junior doctors across England, Health Secretary Jeremy Hunt has said.
Mr Hunt said it had been a "difficult decision" to take but the NHS needed certainty, including in light of the UK's decision to leave the EU.
It comes after junior doctors and medical students rejected a contract brokered between the British Medical Association (BMA) and the Government, with 58% voting against the deal while 42% voted in favour.
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Some 68% of those eligible turned out to vote - around 37,000 junior doctors and medical students.