The Queen will mark Maundy Thursday by distributing alms as part of a tradition dating back to the 13th century.
She will be accompanied by the Duke of Edinburgh for the service at Leicester Cathedral where the Maundy Money will be distributed to 91 men and 91 women - representing each of her 91 years.
The 182 recipients of the Maundy money are senior citizens who will be given the gifts in recognition of the service they have given to the church and their local area.
The Queen will hand two purses - one white and one red - to each person during the service.
The red purse contains a £5 coin, commemorating the Centenary of the House of Windsor and a 50p coin commemorating Sir Isaac Newton, while the white purse will contain uniquely minted Maundy coins, equating in pence to her age.
The Royal Maundy is an ancient ceremony which originated in the commandment Christ gave after washing the feet of his disciples the day before Good Friday.
The Queen last visited the East Midlands city in March 2012 as part of her Diamond Jubilee tour, while the cathedral is the final burial place of King Richard III, whose remains were discovered in the city in September 2012.