New homes in South Yorkshire will be demolished after the Government confirmed the route of HS2.
Properties on the Shimmer housing estate in Mexborough will be bulldozed to make way for the high-speed railway, the Department for Transport (DfT) said.
Residents will lose their homes because ministers decided the line should serve the existing Sheffield city centre station after proposals to run trains to Meadowhall shopping centre were shelved.
Labour's Rotherham MP Sarah Champion said she was "furious" because South Yorkshire "won't get a proper stop".
The DfT said 16 properties on the Shimmer estate will be demolished.
Some respondents to a Government consultation had argued that the plans should take into account all 216 homes originally planned at the site.
Transport Secretary Chris Grayling's decision on the route from Crewe to Manchester and Birmingham to the East Midlands and Leeds confirms six of the seven changes included in the November consultation.
Mr Grayling decided not to proceed with a proposal to move the line to the east of Measham, Leicestershire.
The railway will run to the west of the village with a viaduct extended to mitigate the impact on commercial properties.