Walter Vance, a 61-year-old pharmacist who reportedly suffered from a prior heart condition, later died in hospital, reports MSNBC.
Witnesses say some shoppers ignored and even walked over the man's body as they continued to shop, reports the New York Daily News.
Friends and co-workers saddened to learn of his death, expressed outrage over the way he was treated by shoppers.
"Where is the good Samaritan side of people?" Vance's co-worker Sue Compton told WSAZ-TV.
"How could you not notice someone was in trouble? I just don't understand if people didn't help what their reason was, other than greed because of a sale."
Gawker points out there is no legal obligation to come to someone's rescue, only a moral one.
While some news organizations say that no one helped the collapsed man, his wife refuted this report.
Lynne Vance said six nurses shopping in the store came to her husband's rescue and performed CPR until paramedics arrived, notes the Sunday Gazette Mail.
This wasn't the only incident to taint America's biggest shopping day.
While one customer sprayed fellow shoppers with pepper spray so she could snag a video game, another scenario involved an exhausted Target worker accidentally driving her car into a canal after working the Black Friday midnight shift.
Here are what people bought last year: