The GOT actress will launch the new Eau de Toilette for the brand in September.
Clarke’s co-star Kit Harington was also announced as the face of The One for Men earlier this month.
“Emilia Clarke embodies perfectly the Dolce & Gabbana woman: she is radiant and lively,” said Domenico Dolce and Stefano Gabbana.
“Her personality and natural beauty will capture the essence of this new campaign: joyful, spontaneous and full of life. She is The One!”
Earlier this month Clarke guest edited The Huffington Post UK as part of our month-long All Women Everywhere project and blogged about ‘The New Sexy’, discussing feminism, equality and being a girl-boss with sincere honesty.