DNA Analysis Could Predict How Long You Will Live, Research Suggests

Dna

First Posted: 10/01/12 07:18 GMT Updated: 10/01/12 07:26 GMT   PA

An individual's DNA can help predict how long they will live early on in life, new research suggests.

Scientists studying zebra finches found the best indicator of longevity came from examining a piece of DNA called a telomere when the birds were 25 days old.

Telomeres occur at the ends of the chromosomes, which contain an individual's genetic code.

They are caps on the end of chromosomes that protect them from damage and function a bit like the plastic caps at the end of shoelaces.

This method of DNA protection is the same for most animals and plants, including humans, and the eventual loss of the telomere cap is known to cause cells to malfunction.

For the first time, scientists have now measured telomere length in the same individuals throughout their life span from early life onwards.

Researchers, led by a team at the University of Glasgow, studied 99 zebra finches whose lifespan ranged from 210 days to almost nine years.

They took blood samples at intervals to measure telomere length.

The scientists found that the best predictor of longevity was telomere length at 25 days.

It is known that the variation in telomere length is partly inherited, but also varies due to differences in environmental factors such as exposure to stress.

Professor Pat Monaghan, who led the team, said: "Our study shows the great importance of processes acting early in life.

"We now need to know more about how early life conditions can influence the pattern of telomere loss and the relative importance of inherited and environmental factors. This is the main focus of our current research."

The study was published yesterday in the Proceedings of the National Academy of Sciences USA.

The work was funded by the European Research Council, with additional support from the UK Natural Environment Research Council, the Wellcome Trust and the US National Science Foundation.

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An individual's DNA can help predict how long they will live early on in life, new research suggests. Scientists studying zebra finches found the best indicator of longevity came from examining a p...
An individual's DNA can help predict how long they will live early on in life, new research suggests. Scientists studying zebra finches found the best indicator of longevity came from examining a p...
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jf12
When I saw her I marveled greatly.
04:23 PM on 01/12/2012
Doctor: I'm very sorry to tell you that I think you have only 27 more years to live.
Patient: I demand a second opinion!
Doctor: Ok, I think you're ugly, too.
03:54 PM on 01/10/2012
Welcome to Gattica...

I think that test is faulty in that it rules out lifestyle and environmental factors.
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Blackspeare
03:40 PM on 01/10/2012
Reminds of the runner Jim Fixx, who believed that we are born with a set number of heartbeats and when you reach that number it's all over. He claimed that by running he substantially reduced his resting heartbeat and thus extended his life span. Unfortunately, he had a heart attack while running----the one thing he didn't know was the final number, but nonetheless, he may have been right.
04:19 PM on 01/10/2012
It is ironic that Fixx died while running. He was borderline obese before he began his running and exercise regimen that led him to become a near world class distance runner. it was blockage in the primary arteries supplying blood to his heart that caused the attack.

It was also ironic that he fell on a hillside that kept him on an approximate 45 degree angle with his head well above his feet. Had he fallen on level ground or with his head lower than his upper body, doctors speculated that he might have lived.

I guess when God says it's your time, it's a done deal.

I run to relieve stress. I know it helps me feel better at least.
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NewLiberals
Make a Difference
02:51 PM on 01/10/2012
How much do you want to bet this research is funded by Insurance Companies?

Years ago when I took out a sizable life insurance policy I had to submit to a blood sample being drawn for "drug testing". Back then I would never had considered what could be done to use your blood as a crystal ball to your future.

We're going to need to start stipulating what can and can not be done with our DNA samples.

Maybe a Fifth Amendment tack would work.
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drsolo
Progressive Wisconsin
02:52 PM on 01/10/2012
Ever seen the movie GATTACA?
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HUFFPOST COMMUNITY MODERATOR
iskra
Natural enemy of sharks and tro//s
02:42 PM on 01/10/2012
Except for that bus....
02:36 PM on 01/10/2012
I will live until the day I die.
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forestnfama
A Jimi Hendrix Woodstock Veteran
04:38 PM on 01/10/2012
Yes and I was born at a very very early age......
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heartsmindsvision
02:04 PM on 01/10/2012
Very Inteeeeeeeeresting??
01:47 PM on 01/10/2012
They will now be able to estimate how much a person will get in benefits over a life time.
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Phytoresearcher
01:32 PM on 01/10/2012
There are some compounds, such as transmax resveratrol and an extract of astragalus called biospan, which have been shown to up regulate telemerase production in humans. The effect is to protect the telemeres from shortening, and possibly even lengthen them, thus increasing the number of times they can replicate.
01:21 PM on 01/10/2012
A man, in mourning came up to MOHAMMED one morning and said; "Look our prophet; My son was barely a day old when he died.I'm 30 years old. Isn't it a shame? What that child has seen of this world?

To that question, The Glorious Prophet Muhammed replied; "He's seen enough. Since, in eyes of Allah, a day equals to a thousand years. There is really no difference between those souls who have lived a single second or two hundred years. Only Allah knows the best.
avanteguard
Truth, Justice, and the American way
03:44 PM on 01/10/2012
Son, get Jesus before it too late for you!
04:21 PM on 01/10/2012
Sounds like you should "get" Jesus.
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pepper1311
POGS are dirt
12:42 PM on 01/10/2012
I have a manic eight ball that does the same at half the cost. No not the eight ball you people want...
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HekmagaJuximaxx
Shish Kebab, anyone?
02:54 PM on 01/10/2012
Does it jump around uncontrollably? Perhaps Lithium can help
llyd wlsh
chem, nuke, bio hazard
11:32 AM on 01/10/2012
they blinded me with science
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11:05 AM on 01/10/2012
This might make sense in a general normal lifespan scenario but does not take into account accidents, illnesses, plagues, murders, depression leading to suicide,catastrophic disasters etc. If you assume that none of these take place then it might have some merit on society as a whole.
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10:57 AM on 01/10/2012
Barring accidents,murder,manslaughter suicide etc......I suggest I could live until I drop dead I predict.
Key words here....Could, Predict and Suggests......sounds a bit vague to me.
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drsolo
Progressive Wisconsin
02:48 PM on 01/10/2012
Key words here....Co­uld, Predict and Suggests..­....sounds a bit vague to me.

That is how scientists write about research and probability. No absolutes.
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03:03 PM on 01/10/2012
Ah ha! I is a scientist and I didn't even know dat I was...... I've impressed meself !!
avanteguard
Truth, Justice, and the American way
03:45 PM on 01/10/2012
Drsolo...exactly why "manmade" global warming is a complete hoax.
10:12 AM on 01/10/2012
But there are several tools on the web that can exactly give your estimated time to your death?

No really, why do you want to know how long you'll live?