A poignant evening is expected at White Hart Lane as Tottenham and Bolton replay their match which was abandoned after Fabrice Muamba collapsed 10 days ago.
Muamba suffered a cardiac arrest and remains in hospital, but the 23-year-old is making "encouraging progress", say doctors.
The score was at 1-1 when the midfielder fell in the 41st minute, with Kyle Walker equalising for Spurs after Gareth Bale's own goal gave the visitors a sixth minute lead.
Howard Webb however abandoned the game to nationwide approval after Muamba's state was recognised as critical.
Spurs go into this match without a win in five league games and just two victories in as many months. Their last triumph came against Stevenage in their FA Cup fifth-round replay.
Striker Jermain Defoe, a friend of Muamba's, visited the ex-England Under-21 international in hospital the day after he was admitted to hospital.
Bolton played their first fixture after Muamba's collapse against Blackburn at the weekend. Two goals from David Wheater proved enough in a crucial 2-1 win against their fellow Lancashire strugglers.
the club's match last Tuesday against Aston Villa was postponed, but manager Owen Coyle said last week "we have to go and play".
"We will do our best, as we always try to do. Will it be emotional? Of course," BBC Sport reported the Scot as saying.
"But I can't say how it is going to be until we are physically there."