The 41-year-old wowed in a plunging print halter-neck gown with black satin trim and cut-out detailing at the waist. She's a sister who knows how to strike a pose too.
Cameron did that classic, understated thing and wore a silk black tunic top and pencil skirt paired with black strap stilettos. She completed her look with a killer red lipstick and those signature glossy tresses.
Christina (who made her first red carpet appearance since welcoming her baby daughter, Summer) went all out in a red long-sleeved, floor-length dress and Christian Louboutin heels.
Post-baby, the 33-year-old singer looked pretty hot arriving with fiancé Matthew Rutler, but Kate just had that elegant edge.
The awards ceremony, hosted by Seth MacFarlane at Hangar One, a former shelter for NASA airships in California, paid tribute to accomplished scientists and mathematicians. It was launched two years ago by Russian billionaire venture capitalist Yuri Milner, Facebook founder Mark Zuckerberg and Google co-founder Sergey Brin.
LOVE KATE'S STYLE? The lady definitely knows how to piece together a look-at-me-do-stunning ensemble. Take a click through this gallery to see some of our favourite Beckinsale looks for glamorous style inspiration.