'Shake It Off'.
The brilliant video, which has been viewed more than 300,000 times, shows the kids busting moves to the country star's hit song with the defiant message that they won't allow sickness to get them down.
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Among the many stars, 15-year-old Halim Smith who needs a liver transplant told CBS3: "Even though we're in the hospital we can still have fun you know.
"Shake all the bad stuff off and think everything in a positive way, don't think of everything as being bad."
Hannah Stetson, 11, has lost half her colon, and making the music video was a welcome distraction.
The video was created by the Child Life Department and coordinates things like – art, music and pet therapy programmes.
Elise Keels from Child Life said: "They lose so much control when they're here but they're still having fun with our services so they're shaking if off."
The video was done in honour of Child Life Month, recognising the importance of the specialists who help sick children cope and provide emotional support to families.
You can find out more about the hospital and the cause here.