Dementia And Alzheimer's Symptoms Can Hit 'At 45' Research Shows

Middle Age Dementia

Huffington Post UK   First Posted: 06/01/12 06:22 Updated: 06/01/12 08:17

The brain's capacity for memory, reasoning and comprehension can begin to decline from age 45, research has shown.

Previous studies have suggested 60 to be the age people experience a difference in their thinking abilities, but new research which studied more than 7,000 people over a 10 year period suggests differently.

Tasks were set to assess memory, vocabulary, hearing and visual comprehension skills. included recalling in writing as many words beginning with the letter S as possible and as many animal names as could be thought of.

The good news is that vocabulary didn’t wane at all between 45-60. However all other brain function performed poorly in the cognitive tests, which were measured 3 times over 10 years.

In men, there was a 3.6% drop in reasoning after 10 years among those who were aged 45 to 49 at the start of the study and 9.6% among those aged 65 to 70.

In women, the decline was 3.6% and 7.4% in the same age groups respectively.

The authors of study conducted by the Centre for Research in Epidemiology and Population Health in France and University College London in the UK concluded: "Cognitive decline is already evident in middle age (age 45-49)."

They added: "Life expectancy continues to increase, and understanding cognitive ageing will be one of the challenges of this century.

"Poor cognitive status is perhaps the single most disabling condition in old age."

Their research focused on civil servants aged between 45 and 70 at the start of cognitive testing in 1997 to 1999. The results will be published online in the British Medical Journal (BMJ).

Dr Anne Corbett, research manager at the Alzheimer's Society, said that although the study was useful, it didn’t show what caused dementia or what signs would show the decline in health.

"More research is now needed to help us fully understand how measurable changes in the brain can help us improve diagnosis of dementia.

"An early diagnosis is essential as it can provide access to support and potential treatments which can vastly improve people's quality of life."

Over 750,000 people in the UK have a form of dementia, more than half have Alzheimer’s disease. In just ten years a million people will be living with dementia. This will soar to 1.7 million people by 2051.

One in three people die from dementia in the UK.

Dr Simon Ridley, head of research at Alzheimer's Research UK, said: "It's important to note that the group studied here was not representative of the population as a whole, and it would be helpful to see similar studies carried out in a wider sample.

"Previous research suggests that our health in mid-life affects our risk of dementia as we age, and these findings give us all an extra reason to stick to our new year's resolutions.

"Although we don't yet have a sure-fire way to prevent dementia, we do know that simple lifestyle changes - such as eating a healthy diet, not smoking, and keeping blood pressure and cholesterol in check - can all reduce the risk of dementia."

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The brain's capacity for memory, reasoning and comprehension can begin to decline from age 45, research has shown. Previous studies have suggested 60 to be the age people experience a difference in...
The brain's capacity for memory, reasoning and comprehension can begin to decline from age 45, research has shown. Previous studies have suggested 60 to be the age people experience a difference in...
 
 
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16:28 on 21/01/2012
This is a study with far too many unanswered (but important) questions. Who did they study? Sedentary people? Active people? What was their diet like? High in trans fat? High in refined sugar? How did these people spend their time? Watching tv? Doing mindless things? Or being creative, engaging in stimulating and challenging activities? Did these people take any medications? Antidepressants (which have cognitive implications)? Were they meditators? Tell me the Dalai Lama's brain is deteriorating. This study does not jive with the entirety of human history where great masterpieces, groundbreaking theories, and important scientific discoveries were produced by people in middle age. But what it does jive with is our current state of affairs: a sedentary, obese, tv watching, over-medicated public.
I'm not buying it. But then I'm nearly 45. Maybe I'm not thinking clearly.
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18:59 on 06/01/2012
If a person has done little to cultivate their brain and keep their mental acuity, odds are they will start declining sooner. I agree that there are hereditary factors, but some people just don't do anything to stimulate their intellect.
13:57 on 06/01/2012
I don't believe it. What about Professor Stephen Hawking? His is acknowledged as the word's cleverest man. How old is he now? About 65? An amazing intellect. I'm not in his class but I have improved immensely over the years. It's use it or loose it.
15:32 on 06/01/2012
Meta-analysis focus on a greater majority of a given population. Of course there can and will be exceptions but they are very few and far between.
13:44 on 06/01/2012
Wat a lode of robish.I am 63 ad I still hove all mi faciltys. Its like saying 5 out of 4 poople cant do fractions. i fowned thet wen i got to be 60 i got a mega brian serge and i retrained as a nucleear pyschiatrist,( psysacyst?) i didnt fanci the psycho the rapist corse they ofered mi as i didnt like the sownd of it. Anywey, i have just done a cors on ritin for nudepapers, how to becum a journeyman and i passed with filin colors, only cost 600 squits! me next ventore is a cors in erdin cats as i am intrested in animal welfair. So whoos stupit now. I am proove that lief beggins at 60.
15:33 on 06/01/2012
LOL!!
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HUFFPOST COMMUNITY MODERATOR
Sepulchre
A neutron walks into a bar...
12:33 on 06/01/2012
This study based on the criteria proves nothing. The test group was completely skewed. First they are not testing the general population, only a select group of it, second they didn't test anyone under 45 to set a correct baseline and determine if decline might actually start earlier than they had hypothesized. This conclusion is a joke, and poor science.
11:56 on 06/01/2012
Has anybody else noticed how old many American politicians are. Jimmy Carter for one is still being active. They also have a lot of very old senior judges.
11:36 on 06/01/2012
Unlike our MP's who want us all to work until we drop its a shame we can't establish law that says once you reach 45 you should be reasigned to the Civil Service that way the wiser generation might actually get the UK out of the mess our Gov and their lame brained advisors have put us all in - let the youngsters take care of business and let us take care of the UK - I doubt we would do a worse job -just think about it the country being run by an older generation who have built up a life time of knowledge and experience overseeing a young energetic workforce of go getters - what could possibly go wrong Big Buisness no longer have to make excuses why they wright off the over 45's and the Civil Service gets staffed with people who know all the tricks of the trading when it comes to the shady business practices of the Corporations ; we have already spent a life time playing in their sand box
(Note - no distrespect is ment by this comment to my fellow countrymen who work in the Civil Service - Only to those that despite having the right piece of paper or letters after their name consitantly prove them selves to be completly enept at producing workable policies for this countries Civil Service to follow without appearing to have completly lost their marbles)
11:21 on 06/01/2012
Can't say that I'm quaking over this. Humans live somewhat artificially extended lifespans because of the Neolithic and Industrial Revolutions--less than ten millenia, a blink in evolutionary terms. It's not surprising that the body's systems are taxed after the 30s. However, a healthy diet, exercise, meditation, and Yoga are what I've been doing for a while. Barring bad genes, illness or accidents, I just may enjoy the most of my faculties into my 80s or 90s...perhaps even longer, given the possible trajectory of medical advancements. The most we can do is to live well and be as happy as possible.
13:58 on 06/01/2012
Our neighbour is 95 years old. She likes a drink and she smokes like a chimeny and has all her faculities and a better social life than we do.
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earto44
Defender of planet Erf.
10:47 on 06/01/2012
Squirrel.
10:21 on 06/01/2012
ive noticed a few changes in myself over the years so im just going at life full throttle now and to hell with the future. by the time im licking windows and peeing in plant pots ill be skint so the government can pay to keep me warm as ill have spent my savings having fun.
11:39 on 06/01/2012
The changes must start very early in some, I knew people who were peeing in plantpots when they were students.
10:06 on 06/01/2012
Oh great! Now they have just written off the over 45's for jobs now! Maybe its not being slow its being wise not to answer fast with a wrong answer so they don't get comebacks for giving wrong fast answers like the young! LOL! What happened to wisdom!
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Sickofpoliticians2
here to pissuoff
15:31 on 06/01/2012
the over 45's were written off in the jobs market years ago
19:41 on 06/01/2012
Really! And now we know why the country is in the state that it is! Kids run it! LOL!
Billk29
Justified Ancient of Mu
09:58 on 06/01/2012
I used to know why this happens but i seem to have forgotten.......ooh...look....something shiny.....
HUFFPOST SUPER USER
BuxtonBlueCat
Most beautiful cat in the world! :)
09:57 on 06/01/2012
How old is Diane Abbott?
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HUFFPOST SUPER USER
pepper1311
POGS are dirt
09:46 on 06/01/2012
Not news, early onset dementia has been diagosised for years. poor prognosis.
09:16 on 06/01/2012
'Their research focused on civil servants aged between 45 and 70'
and
'Dr Simon Ridley, head of research at Alzheimer's Research UK, said: "It's important to note that the group studied here was not representative of the population as a whole, and it would be helpful to see similar studies carried out in a wider sample.'

And there we have it ladies and gentlemen - the press taking a statistic completely out of context... again...

Also if the study started with people aged 45 how can one not be sure that the decline starts at 20...

Clearly this study is of little use other than stating the obvious... the older you get the less well your cognitive faculties function...
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HUFFPOST SUPER USER
AtlanticEastWest
"We have met the enemy and he is us."
10:16 on 06/01/2012
You wrote the words out of my keyboard ;o)