A fire in a Brazilian nightclub has killed at least 245 people with fears that the death toll could rise further, initial reports suggest.

The deadly blaze, at the Kiss nightclub in the city of Santa Maria, in the south of Brazil, began when a band lit a flare which ignited sound proofing foam on the ceiling, reports the Guardian.

Around 200 people have been injured.

brazil nightclub fire

Firefighters work to douse a fire at the Kiss Club in Santa Maria city, Rio Grande do Sul state

Fire chief Guido de Melo told the Brazilian website, G1: "Fire services are looking for other victims. We can't give an exact number [of those killed]. People started panicking and ended up treading on each other,"

He added: "We have just taken the fire under control. Now we are removing the bodies."

Rescue services had to smash through walls to reach those trapped inside.

Reports suggest many choked to death or were trampled in the rush to escape the nightclub which only had one exit.

One survivor, Aline Santos Silva, 29, told Globonews TV: "It was really fast. There was a lot of smoke, really dark smoke.

"We were only able to get out quickly because we were in a VIP area close to the door."

There may have been as many as 2000 people in the nightclub at the time of the fire.

The UK's Foreign Office Minister Hugo Swire says thoughts and condolences are with everyone involved in nightclub fire.

“I am deeply saddened by the news of the tragic accident in Santa Maria early this morning.

"My thoughts and sincere condolences are with the families and loved ones of those who have lost their lives, and I wish a swift recovery to the hundreds who are now being treated in hospital.”

WARNING: This gallery contains images some people may find upsetting

Loading Slideshow...
  • ALTERNATIVE CROP OF XSI107.- Relatives of victims react as they wait for news near the Kiss nightclub in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the club while a band was performing. (AP Photo/Ronald Mendes-Agencia RBS)

  • ALTERNATIVE CROP OF XSI108.- Relatives of victims react as they wait for news near the Kiss nightclub in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the club while a band was performing. (AP Photo/Ronald Mendes-Agencia RBS)

  • Relatives of victims react near the Kiss nightclub in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the club while a band was performing. (AP Photo/Ronald Mendes-Agencia RBS)

  • A crowd stands outside the Kiss nightclub during a fire inside the club in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. A blaze raced through the crowded nightclub in southern Brazil early Sunday, killing 245 people as the air filled with deadly smoke and panicked party-goers stampeded toward the exits, police and witnesses said. It appeared to be the world's deadliest nightclub fire in more than a decade.(AP Photo/Roger Shlossmacker)

  • In this photo released by Brazil's Presidency, Brazil's President Dilma Rousseff, left, speaks about a fire that swept through a crowded nightclub killing at least 245 people i a southern Brazil, during a press conference in Santiago, Chile, Sunday, Jan. 27, 2013. Rousseff cut short a visit to Chile early Sunday to return home after the deadly nightclub fire. The fire killed at least 245 people and left at least 200 injured, police and firefighters said. (AP Photo/Brazil's Presidency)

  • A victim of a fire in a club is carried in Santa Maria city, Rio Grande do Sul state, Brazil, early Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the Kiss club in the city of Santa Maria while a band was performing. At least 200 people were also injured. (AP Photo/Deivid Dutra/Agencia Freelancer)

  • ALTERNATIVE CROP OF XSI103.- People help an injured man, victim of a fire in a club in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the Kiss club in the city of Santa Maria while a band was performing. At least 200 people were also injured. (AP Photo/Agencia RBS)

  • People help an injured man, victim of a fire in a club in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. According to police more than 200 died in the devastating nightclub fire in southern Brazil. Officials say the fire broke out at the Kiss club in the city of Santa Maria while a band was performing. At least 200 people were also injured. (AP Photo/Agencia RBS)

  • A man carries an injured victim of a fire at the Kiss club in Santa Maria city, Rio Grande do Sul state, Brazil, early Sunday, Jan. 27, 2013. Firefighters say that the death toll from a fire that swept through a crowded nightclub in southern Brazil has risen to 180. Officials say the fire broke out while a band was performing. At least 200 people ere also injured. (AP Photo/Agencia RBS)

  • Firefighters work to douse a fire at the Kiss Club in Santa Maria city, Rio Grande do Sul state, Brazil, Sunday, Jan. 27, 2013. Firefighters say that the death toll from a fire that swept through a crowded nightclub in southern Brazil has risen to 180. Officials say the fire broke out at the club while a band was performing. At least 200 people were also injured. (AP Photo/Agencia RBS)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. Brazilian President Dilma Rousseff interrupted her visit to Chile. AFP PHOTO / AGENCIA RBS / GERMANO RORATTO / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters work at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. More than 150 people died early Sunday when a fire tore through a nightclub in the southern Brazilian city of Santa Maria during a boisterous student party, police said. Brazilian President Dilma Rousseff interrupted her visit to Chile. AFP PHOTO / AGENCIA RBS / GERMANO RORATTO / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    The victims of a nightclub fire receive medical assistance in a street of Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    People run away as firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. Brazilian President Dilma Rousseff interrupted her visit to Chile. AFP PHOTO / AGENCIA RBS / GERMANO RORATTO / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    The victims of a nightclub fire receive medical assistance in a street of Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. AFP PHOTO / AGENCIA RBS / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    Relatives of victims embrace as they wait for information after a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. More than 150 people died early Sunday when a fire tore through a nightclub in the southern Brazilian city of Santa Maria during a boisterous student party, police said. Brazilian President Dilma Rousseff interrupted her visit to Chile. AFP PHOTO / AGENCIA RBS / LAURO ALVES / BRAZIL OUT (Photo credit should read LAURO ALVES/AFP/Getty Images)

  • BRAZIL-ACCIDENT-FIRE

    People run away as firefighters try to put out a fire at a nightclub in Santa Maria, 550 Km from Porto Alegre, southern Brazil on January 27, 2012. The death toll climbed to 150 early Sunday as firefighters searched the charred remains of the establishment, television Globo reported. Brazilian President Dilma Rousseff interrupted her visit to Chile. AFP PHOTO / AGENCIA RBS / GERMANO RORATTO / BRAZIL OUT (Photo credit should read Germano Roratto/AFP/Getty Images)