The ad in question sees model Georgia May Jagger strike a pose in her underwear while sporting an H-like emblem, similar to the symbol used by Sufi Muslims to refer to Allah, on her skin.
Adding: "To see it disgraced like this for a company to make money is heartbreaking."
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Despite this Roberto Cavalli, which has used the image in campaigns since 2011, claims the symbols are not the same. The designer's stance is also supported by the EU, which last month rejected a request by Sufi groups to ban the company from using the sign.
A spokesman for the fashion house told the Mail Online they were "deeply saddened by the distress expressed by" the Sufi community but that they hope the EU ruling will "convince the Sufist religion of the complete good faith and the groundlessness of their requests".