'Fertility Switch' Could Save Women From Pain Of Infertility Or Miscarriage

First Posted: 17/10/11 16:52 Updated: 17/10/11 18:33

Fertility Breakthrough Found By Scientists

Scientists from the Imperial College London have discovered a ‘fertility switch’ that could help treat infertility and miscarriage in the future.

The study, published in the Nature Medicine journal, discovered an enzyme in the body that determines infertility and the chances of miscarriage, as it acts like a ‘switch’.

The SGK1 protein can determine infertility and the risk of miscarriage simply by how high or low the levels are in the body.

When the female body produces large amounts of SGK1 protein, it increases the chances of infertility but when the levels are low, the chances of miscarriage soar.

The study involved investigating womb lining tissue from 106 women who were struggling to conceive or have had recurrent miscarriages. Researchers found that those who had been trying for a baby for two years or more, had high levels of SGK1 while women who had miscarried, had low levels.

Scientists are hoping these findings could pave the way for new treatments to be designed to reduce infertility and miscarriage rates. It will also be a hopeful finding for those about to embark on in vitro fertilization (IVF) treatment.

"I can envisage that in the future, we might treat the womb lining by flushing it with drugs that block SGK1 before women undergo IVF,” says professor Jan Brosens, who led the study.

"In the future, we might take biopsies of the womb lining to identify abnormalities that might give them a higher risk of pregnancy complications, so that we can start treating them before they get pregnant,” Brosens added.

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Scientists from the Imperial College London have discovered a ‘fertility switch’ that could help treat infertility and miscarriage in the future. The study, published in the Nature Medicine jou...
Scientists from the Imperial College London have discovered a ‘fertility switch’ that could help treat infertility and miscarriage in the future. The study, published in the Nature Medicine jou...
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jf12
When I saw her I marveled greatly.
17:00 on 19/10/2011
There are other common causes of hostile wombs, so this one won't solve all.
19:48 on 18/10/2011
It's nice to hear this, hopefully it will find answers for some women. It is a very heartbreaking experience to have fertility problems. I, myself, have experienced 5 miscarriages, 2 ectopic preg, and it was about 13 years from the miscarriages until I was able to get pregnant again. I had my daughter 3 years ago at the age 38. We tried for one more but that resulted in another ectopic. Now I am unable to get preg again. But I am happy with that, because my daughter is a true blessing to me. And considering that I was unable to afford any treaments and had her, makes her my miracle.
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Jane Su
Proud Pro-Choice Feminist Mother
20:42 on 18/10/2011
Sorry for all that you went through, I had an ectopic a cpl of yrs ago. It was awful, I had to have surgery, and the doctors kept telling me how lucky I was to to be alive. I didn't feel very lucky. Take care of your body.
21:15 on 18/10/2011
Thank you. I had emergency surgeries on both. Had a little internal bleeding on first and was minutes away from rupture on second. Still dealing with the second one. I understand how you "didn't feel very lucky"...I had those feelings on the first one. Sorry for what you've been through. Take care.
18:35 on 18/10/2011
I've had 7 miscarriages, 5 children and it took forever to get pregnant with each of them. Wonder what they would think of me.
16:01 on 18/10/2011
I just do not understand why anyone would want to bring children into the world today. It is
cruel and wicked to subject innocent children to the evils of today's society.
18:27 on 18/10/2011
Pretty sure people have been saying that exact same thing for centuries.
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dancerctry
I love Gardening and Decorating
21:24 on 17/10/2011
How do they explain my 3 miscarriages AND 2 years to get pregnant with my son? The miscarriages were due to low progesterone. Where do they think MY enzyme is?