A young child is in a critical condition after suffering serious injuries in a two-car smash on the M6.
The child was airlifted to hospital following the crash which involved two cars.
His mother and two other siblings were also taken to hospital with minor injuries, West Midlands Ambulance Service said.
Two adults, thought to be in their 20s and 30s, from a second car were also taken to hospital, West Midlands Ambulance Service said.
Emergency services were called to the scene of the accident on the southbound carriageway of the M6 near Hilton Park Services shortly after 4.20pm.
The mother and her three children were travelling in a grey Seat Leon which was in collision with a silver Mercedes C220 carrying a woman and two men between the slip roads of Hilton Services between junctions 11 and 10.
A West Midlands Ambulance Service spokeswoman said: "Crews arrived to find two cars which had been involved in a significant collision.
"A woman and her three children were in one car. Four off duty paramedics from another ambulance service were providing emergency treatment to two of the children.
"Medics and ambulance crews continued treatment on scene; one child suffered a leg injury and was immobilised and stabilised and the other was described as being in a critical condition.
"Both were airlifted to Birmingham Children's Hospital for further emergency treatment. Medics travelled in the helicopter to continue vital treatment en route.
"The third child and the mother suffered relatively minor injuries and were taken by land ambulance to the same hospital.
"Two men and a woman, all believed to be in their 20s and 30s, were out of their car when crews arrived.
"All three were assessed by crews on scene; one man was discharged from treatment whilst the second man and the woman were taken to Walsall Manor Hospital as a precaution."
Staffordshire Police are appealing for witnesses to the incident, which occutred around 4.25pm, to contact them.
The M6 southbound will remain closed while specialist investigators examine the scene of the collision.