Daniel Pelka's mother and stepfather have each been sentenced to life with a minimum tariff of 30 years in jail.
Magdelena Luczak and Mariusz Krezolek were convicted of four-year-old Daniel's murder at Birmingham Crown Court on Wednesday.
Mrs Justice Cox said the sentence reflected the 'incomprehensible brutality by both of you up to his death'.
Daniel was beaten, starved and poisoned with salt by the pair, who hid the abuse by claiming he had an eating disorder.
Then the tragic little boy was left in his room to die for around 33 hours after he suffered a head injury on March 1, 2012.
Luczak, 27, and Krezolek, 34, had denied murder and tried to blame each other for Daniel's death.
The jury convicted the pair in less than four hours. One jury member broke down in tears as the judge made her final comments on the case.
Mrs Justice Cox said the trial had heard 'harrowing details of the unimaginable acts inflicted on Daniel'.
She said she had not seen a 'single sign of genuine remorse' from Luczak or Krezolek.
She told them: "Both of you are in breach of what is probably the most important position of trust - as the parent of a small child."
Daniel's death prompted a serious case review by Coventry's Safeguarding Children Board, with a report due to be published in the next six weeks.
The review will examine why police and social services did not get involved after staff at Daniel's school - Coventry Little Heath Primary School - noticed bruising on his neck and what appeared to be two black eyes.