The 36-year-old pregnant actress appeared on Bravo's Watch What Happens Live to promote her latest film Marvel but ended up talking about the 'Work B*tch' singer.
"I have a huge amount of respect for Britney Spears," Saldana said.
"I've always said this, and I will always continue to say it: She was the one big, big celebrity that I met when I was starting to work in Hollywood, who literally was humble, and whatever was going on in her mind there in her world, it was never about hating her neighbour."
As for what it's really like to make it in the industry? Zoe revealed Britney made the big time without being a hater:
"She was the only pop star at the time - and I can name a lot of prominent figures right now that are today more famous than Britney that literally got to where they were at by hating on Britney, because it was cool at one time to just diss her - and Britney never did that."
Clearly, the pop princess feels the same way about Zoe. Britney responded to Saldana by posting this photo on Instagram.
Think Spears, Saldana and their co-star Taryn Manning circa the teen dream movie with the caption: "@ZoeSaldana is truly the sweetest. Nothing but great memories of working with her."
LOVE ZOE'S STYLE? Check out this gallery all about the American actress.
MORE! Catch up on all the latest Zoe Saldana news right here, YES she's pregnant - but is she really having twins?