The 26-year-old model will host the pop up extravaganza, known as London Fashion Week's little sister, where she will take part in discussions and impart her style advice.
The four day event featuring industry talks, catwalk shows and shopping from 150 brands, will take place on 24 to 27 September at London's Saatchi Gallery.
Caroline Rush CBE, chief executive of the British Fashion Council, said: "Daisy is a fantastic ambassador of British fashion.
"We have worked with her for many years and are delighted that she is joining the London Fashion Weekend team.
"This season is set to be both unmissable and unforgettable with names including Peter Pilotto, House of Holland, Natalie Massenet and Anya Hindmarch already on the line-up."
A front row regular at London Fashion Week and the star of campaigns for Chanel, Burberry and Agent Provocateur, Lowe is one 'It' girl who has earned her style credentials.
She said: "I am so thrilled to be an ambassador for London Fashion Weekend, having worked with Caroline and the British Fashion Council over the years.
"London Fashion Weekend is such an amazing concept, giving people an opportunity to immerse themselves in the fashion world and encouraging visitors to get behind the UK's incredible fashion industry and its designers."
Tickets are priced from £20 and are available now from londonfashionweekend.co.uk