Three people have been arrested following the death of a teenager who is believed to have taken ecstasy in a nightclub.
The 18-year-old fell ill at the Warehouse club in Byker, Newcastle, early on Sunday morning and later died in hospital.
Officers believe she may have taken MDMA - ecstasy - before she became unwell.
Northumbria Police said two men aged 19 and one man aged 21 had been arrested on suspicion of supplying a controlled drug.
Both 19-year-olds have been released on police bail but the 21-year-old remains in custody.
Chief Inspector Phil McConville said: "The initial police investigation into this young woman's death indicates that she may have taken some kind of drug and had a fatal reaction to the substance.
"We believe it may have been MDMA and we need anyone else who was at this nightclub and who may have taken any drugs to go to hospital immediately and get checked out."
He added it was "vitally important" that anyone with information about who supplied the drugs should contact police immediately.