High Cholesterol Could Reduce Couple's Fertility Chances
Struggling To Conceive? This Could Be The Cause
PA/The Huffington Post UK
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Struggling to conceive? It could be down to cholesterol levels.
According to recent research, high cholesterol may reduce infertility - as well as increasing risk of heart disease.
When both partners in a couple had high amounts of cholesterol in their blood it took the longest time to achieve a pregnancy, the research showed.
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It also proved harder for couples to become parents when the woman had high cholesterol but the man did not.
Why cholesterol should affect fertility remains unclear, but the fatty substance is closely involved in the manufacture of sex hormones such as testosterone and oestrogen.
Lead scientist Dr Enrique Schisterman, from the National Institute of Child Health and Human Development, said: "We've long known that high cholesterol levels increase the risk for heart disease. From our data, it would appear that high cholesterol levels not only increase the risk for cardiovascular disease, but also reduce couples' chances of pregnancy.
"In addition to safeguarding their health, our results suggest that couples wishing to achieve pregnancy could improve their chances by first ensuring that their cholesterol levels are in an acceptable range."
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10 More Things You May Not Know About Your Fertility
(01 of10)
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1. Your fertility is mostly determined by genetics, which influences how many eggs you are born with. Doctors believe that the number of eggs you have at birth determines the length of time you will remain fertile. At birth, women have about two million eggs in their ovaries. For every egg ovulated during your reproductive life, about 1,000 eggs undergo programmed cell death. Other things, such as smoking cigarettes and certain types of chemotherapy, can accelerate egg cell death and promote an earlier menopause.
(02 of10)
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2. Regular menstrual cycles are a sign of regular ovulation.Most women have regular cycles lasting between 24 and 35 days. This is usually a sign of regular, predictable ovulation. Women who do not ovulate regularly have irregular menstrual cycles. Those who do not ovulate at all may have a genetic condition called polycystic ovarian syndrome (PCOS).
(03 of10)
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3. Basal temperature charting does not predict ovulation.An older method of tracking ovulation involves taking your oral body temperature each morning before getting out of bed. This is called basal body temperature. This method is used to spot a rise in basal temperature, which is a sign that progesterone is being produced. The main problem with using this method is that your temperature rises after ovulation has already occurred. This makes it more difficult to time intercourse at an optimal time for conception. A better method is to use over-the-counter urine ovulation predictor test kits such as Clearblue Easy. These kits test for the hormone that prompts ovulation, which is called luteinizing hormone (LH).
(04 of10)
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4. Most women with blocked fallopian tubes are completely unaware they may have had a prior pelvic infection.About 10 percent of infertility cases are due to tubal disease, either complete blockage or pelvic scarring causing tubal malfunction. One major cause of tubal disease is a prior pelvic infection from a sexually transmitted disease such as chlamydia. These infections can cause so few symptoms that you may be completely unaware your tubes are affected. This is why fertility physicians will order a dye test of the tubes, called a hysterosalpingogram (HSG), if you have been trying and failing to conceive for 6 months or longer.
(05 of10)
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5. In most cases, stress does not cause infertility. Except in rare cases of extreme physical or emotional distress, women will keep ovulating regularly. Conceiving while on vacation is likely less about relaxation than about coincidence and good timing of sex.
(06 of10)
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6. By age 44, most women are infertile, even if they are still ovulating regularly. Even with significant fertility treatment, rates of conception are very low after age 43. Most women who conceive in their mid-40's with fertility treatment are using donated eggs from younger women.
(07 of10)
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7. Having fathered a pregnancy in the past does not guarantee fertility. Sperm counts can change quite a bit with time, so never assume that a prior pregnancy guarantees fertile sperm. Obtaining a semen analysis is the only way to be sure the sperm are still healthy!
(08 of10)
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8. For the most part, diet has little or nothing to do with fertility. Despite popular press, there is little scientific data showing that a particular diet or food promotes fertility. One limited study did suggest a Mediterranean diet with olive oil, fish and legumes may help promote fertility.
(09 of10)
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9. Vitamin D may improve results of fertility treatments. A recent study from the University of Southern California suggested that women who were undergoing fertility treatments, but had low vitamin D levels, might have lower rates of conception. This vitamin is also essential during pregnancy. At Pacific Fertility Center, we recommend our patients take 2,000-4,000 IU per day.
(10 of10)
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10. Being either underweight or overweight is clearly linked with lowered levels of fertility. The evidence in recent years is that obesity is clearly linked with a longer time to conception. Having a body mass index less than 18 or over 32 is associated with problems ovulating and conceiving, as well as problems during pregnancy.
The study involved 501 couples from Michigan and Texas taking part in an investigation into links between fertility and environmental chemicals and lifestyle.
Volunteers provided blood samples which were tested for total "free" cholesterol and did not distinguish between different "good" and "bad" sub-types.
Of the two main forms of cholesterol, high density lipoprotein (HDL) is known to benefit the heart while low density lipoprotein (LDL) has a harmful effect.
Couples' chances of conceiving over up to one year were estimated using a statistical measure called the fecundability odds ratio (FOR).
Generally, higher cholesterol levels were associated with longer times to pregnancy and lower FORs. Compared with partners who both had cholesterol in the normal range, couples in which the woman's cholesterol was raised but the man's was not took longer to achieve pregnancy.
Those in which both partners had high cholesterol levels took the longest of all.
The research, published in the Journal of Clinical Endocrinology and Metabolism, took account of differences in race, age, body mass index (BMI) and education.
With standard cholesterol tests, low levels of HDL compared with LDL are said to signify an increased risk of heart disease.
Dr Schisterman said high free cholesterol levels were likely to indicate an unfavourable HDL to LDL ratio.