Large swathes of the country are due to be hit with "thundery downpours" over the next two days.
The Met Office has issued yellow weather warnings for rain covering the East Midlands, East Anglia, London and the South East coast.
It said some parts of the country could get 40mm of rain in four hours, with the weather warnings lasting into Wednesday.
"An area of rain with possible thundery downpours is expected to develop along a zone from central southern England through the South and East Midlands to Lincolnshire and possibly affecting some northern and western parts of East Anglia during Tuesday morning," the Met Office said.
"Heavy showers will then develop during Tuesday. Where these occur they are likely to be slow moving and perhaps thundery.
"Some areas may miss the showers entirely whilst others could see two to three hours of heavy rain.
"Where this occurs some disruption is possible such as localised flooding of roads."
The warning comes three weeks after heavy rain lashed the country and led to flash flooding in the coastal village of Coverack.
Fifty properties were affected and several people had to be rescued from their homes from the village in Cornwall.