Scientists have developed a drug they claim could cure cancer, after discovering a single antibody that has been found to shrink seven common types of the disease.
A treatment that targets a protein responsible for blocking the immune system from protecting the body against cancer tumours, has been successfully trialled on laboratory mice.
The drug could slow the growth of cancer tumours and, if taken early enough, even offer a cure, the researchers claim.
The results, published in the Proceedings of the National Academy of Science, reveal the drug successfully blocked the harmful CD47 protein and shrunk human breast, ovary, colon, bladder, brain, liver and prostate tumours which had been implanted into the mice.
The ‘miracle drug’ works by targeting and blocking the CD47 protein - a biomarker that stops the immune system doing its job by telling it to kill healthy blood cells instead of protecting them. The cancer tumour uses this protein to protect it from being destroyed.
Although this technique was discovered a decade ago by biologist Irving Weissman from Stanford University School of Medicine and is already used to treat leukemia and lymphoma, this is the first time research has suggested that it could be just as effective with other types of cancer tumours.
Talking to Science, Weissman, who participated in the study, said: “What we’ve shown is that CD47 isn’t just important on leukemia and lymphomas. It’s on every single human primary tumour that we tested.
However, although the researchers have been given multi-million dollar funding to extend their research from mice to humans, they added that it is unlikely the drugs will available anytime soon.
"We have enough data already, that I can say I'm confident that this will move to phase I human trials,” added Weissman.
Responding to the findings, Dr Kat Arney from Cancer Research UK, told HuffPost Lifestyle: "While the headlines may promise a miracle cure, this ‘wonder drug’ is still at its earliest stages and has only been shown to work in the lab and in mice.
“But it’s certainly an interesting and potentially exciting approach, and we look forward to seeing the results of further work to find out whether anti-CD47 can actually treat cancer in patients safely and effectively.”
Dr Richard Francis from Breakthrough Breast Cancer, added: “It’s exciting that further research is planned into this promising new avenue for cancer treatment. We look forward to finding out whether this drug will be safe and effective for breast cancer patients. However, research so far has only been carried out in mice and it will be several years before we know if humans can benefit.
"We’d encourage anyone with questions about their breast cancer treatment to speak to their doctor.”
A twice-daily skin cancer drug almost doubles the survival times of advanced cancer patients, American scientists have discovered. Researchers from the Jonsson Cancer Center at the <a href="http://www.universityofcalifornia.edu/" target="_hplink">University of California</a>, found that advanced melanoma cancer sufferers lived on average of 16 months after receiving the vemurafenib drug. Read the full story here. <a href="http://www.huffingtonpost.co.uk/2012/02/23/skin-cancer-drug-zelboraf-doubles-survival-times_n_1295896.html?ref=uk-lifestyle" target="_hplink"><strong>Read the full story here</strong></a>
Scientists have discovered five new genes that cause heart attacks and strokes and hope these findings will enable them to pinpoint when the attacks will strike. The researchers, from <a href="http://www.qmul.ac.uk/" target="_hplink">Queen Mary University</a> of London, identified five generic variants that trigger heart attacks and strokes after investigating blood pressure measurements of 25,000 participants. The aim of the study was to look into the role that genes play in hypertension and high blood pressure. <strong><a href="http://www.huffingtonpost.co.uk/2011/11/18/test-predicts-heart-attack-and-stroke_n_1101174.html" target="_hplink">Read the full story here</a></strong>.
American scientists have discovered a potential new drug that could help fight against Alzheimer's disease. Neuroscientists from the <a href="http://casemed.case.edu/" target="_hplink">Case Western Reserve University School of Medicine</a> discovered that a skin cancer drug called bexarotene appears to reverse cognitive and memory deficits associated with Alzheimer's when tested on lab mice. <a href="http://www.huffingtonpost.co.uk/2012/02/09/bexarotene-cancer-drug-prevents-alzheimers_n_1265726.html" target="_hplink"><strong>Read the full story here</strong></a>.
A "personalised" pill for advanced skin cancer that can extend life has been approved for use in the UK. The drug, vemurafenib, only works for patients with a specific variant of the BRAF gene. <a href="http://www.huffingtonpost.co.uk/2012/03/14/personalised-skin-cancer-drug-created_n_1344010.html " target="_hplink"><strong>Read the full story here</strong></a>.
The genetic code of the most common form of hereditary breast cancer has been mapped for the first time, offering hope for diagnosis and treatment of the disease in the future. Researchers say they have "fully sequenced" the DNA of two breast cancers caused by a faulty BRCA1 gene, which is responsible for aggressive and highly drug-resistant tumours. <a href="http://www.huffingtonpost.co.uk/2012/02/24/genetic-breakthrough-breast-cancer-hope_n_1299330.html" target="_hplink"><strong>Read the full story here</strong></a>.
Scientists from the <a href="http://www.northwestern.edu/" target="_hplink">Northwestern University</a> in Chicago have come one step closer to developing a potential cure for peanut allergies, by creating an immune system tolerant to peanuts. The researchers found that they can switch off potentially deadly peanut allergy attacks by tricking the immune system into tolerating nut proteins, and not seeing them as a threat to the body. <strong><a href="http://www.huffingtonpost.co.uk/2011/10/11/peanut-allergies-has-a-cure-been-found_n_1004615.html" target="_hplink">Read the full story here</a></strong>.
A breakthrough lung cancer detection test is set to be trialled on smokers for the first time in Scotland. If successful, cancers could be identified five years earlier than by current detection methods. <a href="http://www.huffingtonpost.co.uk/2012/03/23/breakthrough-lung-cancer-detection-test-trialled_n_1374925.html " target="_hplink"><strong>Read the full story here</strong></a>.
Sleepless nights could soon be a thing of the past as scientists discover a key chemical trigger that suppresses sleep and wakes people up. Researchers from <a href="http://www.bu.edu/" target="_hplink">Boston University </a>found that when the body has too little of the calcium kinase enzyme, it causes the brain to nod off to sleep. <strong><a href="http://www.huffingtonpost.co.uk/2011/11/23/insomnia-cure-a-step-closer-after-enzyme-discovery_n_1109969.html" target="_hplink">Read the full story here</a></strong>.
A new treatment for breast cancer has been discovered after scientists found that breast tumours can be killed in minutes - by boiling them. The latest treatment, known as Preferential Radio-Frequency Ablation, uses a targeted electrical current that heats, or 'boils' the tumour to 70 to 90c (160 to 190f). <strong><a href="http://www.huffingtonpost.co.uk/2011/11/22/boiling-breast-cancer-tumours-kills-them-in-minutes_n_1107632.html" target="_hplink">Read the full story here</a></strong>.
British scientists have developed a revolutionary breast-screening system that uses anti-landmine technology to detect cancer in seconds. The radio-wave scanner is safer, cheaper and less painful than traditional mammogram X-rays, and unlike the current system, can be used on women of all ages. <a href="New Scan Detects Breast Cancer In Seconds Using Anti-Landmine Technology " target="_hplink"><strong>Read the full story here</strong></a>.
Breakthrough research involving a brain transplant of stem cells could offer hope for the treatment of both autism and Parkinson's disease. The study, from <a href="http://www.harvard.edu/" target="_hplink">Harvard University</a>, has already proven successful with mice. Scientists transferred healthy stem cells from mouse embryos into the brains of adult mice who were unable to use leptin, a hormone that tells the body when to stop eating. <strong><a href="http://www.huffingtonpost.co.uk/2011/11/25/stem-cell-hope-autism-parkinsons_n_1112738.html" target="_hplink">Read the full story here</a></strong>.
A stomach implant that can trick the brain into thinking the stomach is full is the latest hi-tech gadget that experts hope will help fight the flab and beat obesity. The <a href="http://www.abiliti.com/" target="_hplink">Abiliti</a>, or 'Gastric Pacemaker', is a credit card-sized implant, inserted using keyhole surgery, which detects when food has been eaten and sends signals to the brain to create the feeling of fullness. <strong><a href="http://www.huffingtonpost.co.uk/2011/11/08/gastric-pacemaker-beat-obesity_n_1082081.html" target="_hplink">Read the full story here</a></strong>.
Scientists from the <a href="http://www3.imperial.ac.uk/" target="_hplink">Imperial College</a> London have discovered a 'fertility switch' that could help treat infertility and miscarriage in the future. The study, published in the <a href="http://www.nature.com/nm/index.html" target="_hplink">Nature Medicine</a> journal, discovered an enzyme in the body that determines infertility and the chances of miscarriage, as it acts like a 'switch'. <strong><a href="http://www.huffingtonpost.co.uk/2011/10/17/new-hope-for-women-struggling-to-conceive_n_1015554.html" target="_hplink">Read the full story here</a></strong>.
Eviplera, a new once-daily pill for the treatment of HIV has been made available in 27 countries of the European Union following approval by the <a href="http://www.ema.europa.eu/ema/index.jsp?curl=/pages/home/Home_Page.jsp&jsenabled=true" target="_hplink">European Medicines Agency</a>. The new drug, from <a href="http://www.gilead.com/" target="_hplink">Gilead Sciences</a>, combines three antiretroviral treatments in a single tablet so HIV patients only need to take one tablet a day to treat their condition. <strong><a href="http://www.huffingtonpost.co.uk/2011/12/01/world-aids-day-2011-new-once-daily-pill-available-in-uk_n_1122590.html" target="_hplink">Read the full story here</a></strong>.
Scientists believe that a potent Alzheimer's vaccine jab could be the secret to preventing the disease developing from its early stages. Researchers from<a href="http://gumc.georgetown.edu/" target="_hplink"> Georgetown University Medical Center</a> in Washington found that an antibody for Alzheimer's disease is more likely to trigger inflammation in the brain the later it is given and that it could potentially be prevented, as long as the vaccine is taken during the very early stages of the disease. <strong><a href="http://www.huffingtonpost.co.uk/2011/11/16/potent-alzheimers-vaccine-could-prevent-disease_n_1096670.html" target="_hplink">Read the full story here</a></strong>.