Jeremy Hunt will give evidence on how he handled News Coporation's wish to take over BSkyB when he appears before the Leveson inquiry on Thursday.
The culture secretary faces renewed calls to resign from Labour after it was revealed that he lobbied the prime minister to support the Murdoch bid before being accepting the role as a supposedly impartial adjudicator of the decision.
Hunt has also been accused of misleading parliament after he told MPs he had no informal contact with News Corp while he was taking the decision only for evidence to come to light that suggested otherwise.
David Cameron has defended giving Hunt responsibility for the decision on News Corporation's takeover of BSkyB.
Hunt sent a memo to the prime minister arguing the case for the bid just weeks before being given the role but Mr Cameron insisted he acted "impartially" once he was responsible for the decision.
Cameron said: "I don't regret giving the job to Jeremy Hunt, it was the right thing to do in the circumstances, which were not of my making."
The prime minster told ITV's This Morning: "The crucial point, the really crucial point, is did Jeremy Hunt carry out his role properly with respect to BSkyB and I believe that he did."
Hunt will be joined next week at the inquiry by several of his cabinet colleagues.
On Tuesday education secretary, and former News Corp owned Times journalist Michael Gove will give evidence. He will be followed by home secretary Theresa May.
While on Wednesday Leveson will hear from business secretary Vince Cable. The Lib Dem minister initially had responsibility for overseeing the BSkyB bid but was stripped of the job after he was secretly filmed expressing fierce opposition to News Corporation.
David Cameron decided that as Cable was not a neutral arbiter of the bid he could not take the decision and handed it to Hunt - despite knowing he had expressed support for Murdoch.
Leveson will also hear from justice secretary Ken Clarke on Wednesday. On Thursday the inquiry heard that Clarke found some of his ministerial work "trying" and may not stay in front line politics for much longer.
On Monday the inquiry will take evidence from former Labour prime minister Tony Blair. He is likely to be quizzed over whether he was too close to Rupert Murdoch and News International during his time in office.
Prime Minister David Cameron
Deputy Prime Minister Nick Clegg
Chancellor George Osborne
Foreign Secretary William Hague
Health Secretary Jeremy Hunt
After a stressful year in the DCMS, Jeremy Hunt moves from Culture to Health, replacing Andrew Lansley.
Home Secretary Theresa May
Cabinet Office Minister Francis Maude
Chief Secretary To The Treasury Danny Alexander
Minister without Portfolio, Ken Clarke
Having stepped down from the Justice Department, Clarke is supposedly staying in Government rather than hanging up his boots. Chris Grayling will replace him as Justice Secretary.
Justice Secretary Chris Grayling
Chris Grayling, formerly in the Department of Work and Pensions, will step up to hold the job vacated by Ken Clarke.
Culture Secretary Maria Miller
Maria Miller has taken up the DCMS job after Jeremy Hunt moved to the Department of Health. Miller is one of the few new faces in the cabinet.
Defence Secretary Philip Hammond
Communities Secretary Eric Pickles
Education Secretary Michael Gove
Minister for Internation Development, Justine Greening
Greening, who has been subject to plenty of rumours since her fallout over a potential third Heathrow runway. Greening was in No 10 for over an hour on Tuesday, presumably arguing her case and battling to stay in the cabinet. She will now take over Andrew Mitchell's spot at DfID.
Transport Secretary Patrick McLoughlin
McLoughlin, who has spent the past two years handling backbench rebels as Chief Whip, moves to the DfT, taking over from under-pressure Justine Greening. Greening has yet to be moved.
Energy Secretary Ed Davey
Attorney General Dominic Grieve
Cabinet Office Minister Oliver Letwin
Warsi, one of the earlest victims of the reshuffle, has been ousted as party co-chairman and is to be replaced by Grant Shapps. Warsi instead moves to to the Foreign Office as a junior minister, while also working as faith and communities minister.
Party Co-Chairman Grant Shapps
Shapps, who was the housing minister, is bumped up to party chairman, taking over from the demoted Sayeeda Warsi.
Environment Secretary Owen Paterson
Spelman leaves her post, to be replaced by the former Northern Ireland secretary Owen Paterson.
Work And Pensions Secretary Iain Duncan Smith
Leader of the House Andrew Lansley
Despite recently setting in motion huge overhauls to the NHS, Lansley has been moved to fill Sir George Young's spot as Leader of the House. Jeremy Hunt will succeed him in the Department of Health.
Business Secretary Vince Cable
Northern Ireland Secretary Theresa Villiers
Theresa Villiers, who gave nothing away as she approached Parliament with a wide smile on her face on Tuesday, replaces Owen Paterson. Paterson has moved to Defra.
Welsh Secretary David Jones
Cheryl Gillan was one name always likely to be taken off the list, and she is replaced by David Jones, who served beneath her as a Minister for Wales.
Scottish Secretary Michael Moore
Chief Whip Andrew Mitchell
Andrew Mitchell has moved moved from the Department for International Development to the role of Chief Whip, replacing Patrick McLoughlin.
Lords Leader Lord Strathclyde