The 53-year-old soap star is keen to break down the stigma around the disease after a viewer told her not to come near them because they might "catch" HIV.
Speaking to The Mirror, Charlie said she told the man: "‘You don’t get HIV from touching somebody – you get it from having unprotected sex and that’s not going to happen is it, kiddo?’ and he meekly said no.”
In a controversial storyline, Charlie’s character was diagnosed with HIV after a fling in Portugal.
"I hope people will have sympathy with Val and have a little think about themselves and their sexual health.”
Charlie first joined 'Emmerdale' in 2004. This is set to be one of her biggest storylines to date and will bring HIV back into soap viewers' minds.
The disease was last covered substantially in Mark Fowler's AIDs storyline in 'EastEnders' back in 2004.