And the results are, perhaps unsurprisingly, both cacophonous and brilliant.
As the National Zoo in Washington, DC explains on YouTube: these Asian small-clawed otters were given the keyboard as part of their '#ZooEnrichment' initiative.
"The otters are given the choice to play the keyboard or just sit back and enjoy the show - engaging their sight, touch, and hearing senses," they write.
We must say, the little guy in the middle is particularly impressive. Although, of course, he's no Keyboard Cat...