Arturo Vidal, coveted by Manchester United, will "certainly leave" Juventus, according to agent Andrea D'Amico.
Vidal has returned to Juve for pre-season, however his future remains enshrouded in doubt after coach Antonio Conte resigned last month and was replaced by former AC Milan coach Massimiliano Allegri.
The 27-year-old Chile international and teammate Paul Pogba have both been linked with departures this summer and the speculation is set to rumble on.
Vidal has won the Scudetto three times in three years with Juve
Speaking on Sky Italia, D'Amico, whose represents Juve attacker Sebastian Giovinco, said: "Vidal and Pogba? One of the two will leave. I’ll go a step further I’m convinced Vidal will certainly leave."
Although their interest has cooled, United held informal talks with Vidal's representatives earlier this year and the midfielder was scouted by David Moyes, who also recently confirmed he would have tried to bring Pogba back to Old Trafford.
Louis van Gaal is a confirmed admirer of Vidal, and saw him at close hand during his two years as Bayern Munich manager, when Vidal was playing for Bayer Leverkusen.
United have made just one addition to their much-maligned midfield this summer when Ander Herrera joined for £29 million from Athletic Bilbao.
Michael Carrick endured arguably his worst season at the club under Moyes but he faces up to three months out with an ankle injury, leaving Marouane Fellaini, Tom Cleverley and Darren Fletcher as the only other experienced central midfielders.
United are ready to cut their losses of Fellaini and Napoli are interested, while Cleverley and Fletcher are an uninspiring duo who are both out of contract next year, as is Carrick. The ostracised Anderson, meanwhile, is unlikely to play for the club again.
Patrice Evra completed his move to Juventus from United on Thursday after eight-and-a-half years at Old Trafford.