The quarterback is currently receiving treatment for his injuries at the Carolinas Medical Center.
Witness Tony Douglas said he saw the Dodge pick-up collide with a Buick. He said the truck flip several times before coming to rest on the passenger side.
Cam Newton being loaded into ambulance https://t.co/Sc2wK6KGJg— Jonathan Jones (@jjones9) December 9, 2014
Reports say Newton is in high spirits and has two transverse process fractures in his lower back.
A statement by the Panthers likened the injury to one suffered by Dallas Cowboys quarterback Tony Romo, who missed one game as a result.
Cam Newton is in fair condition and undergoing tests at Carolinas Medical Center and will remain there overnight for observation.— Carolina Panthers (@Panthers) December 9, 2014
Further testing revealed that Cam Newton has two transverse process fractures in his lower back and no further internal injuries.— Carolina Panthers (@Panthers) December 9, 2014
The player was the NFL's overall top draft pick in 2011, and has one year left on his contract with the Panthers.
Charlotte-Mecklenburg Police are investigating the cause of the crash.