Teenager Born With HIV In Remission For 12 Years, Despite Stopping Medication

Teen Born With HIV In Remission, Despite Stopping Medication
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In a world first, a French teenager who was born with HIV is in remission, having stopped taking medication for the disease 12 years ago.

The 18-year-old, who's identity remains confidential, is the first person in recorded history to have gone into long-term remission from having the disease at birth.

The news brings hope to people suffering from HIV and those who are working to find a cure around the world, but some experts are warning that this is just one case and far more research around the subject is needed.

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Doctors presented the details of the French teenager's case at an International AIDS Society (IAS) conference in Vancouver on Monday.

The young woman was infected with HIV from her mother, either towards the end of pregnancy or during childbirth, they confirmed.

The teen does not have the genetic factors associated with natural control of infection that have previously been investigated.

After she was born, the girl was given the standard six weeks of treatment, but also received four additional anti-retroviral drugs aged three months.

Her family decided to stop the treatment when she was almost six years old for reasons that are unknown, but twelve years later, the virus levels in her bloodstream are too low to be measured.

"It's likely that this girl has been in virological remission for so long because she received a combination of anti-retrovirals very soon after infection," Dr Asier Saez-Cirion from the Institut Pasteur in Paris said, according to the BBC.

"With this first, highly documented case of this young woman, we provide the proof of concept that long-term remission is possible in children, as in adults. However, these cases are still very rare. The woman is living normally. Her case is unique but had gone unnoticed, even among clinicians in France."

Scientist Sharon Lewin, who co-chaired a talk earlier this week on finding a cure for HIV, told the Telegraph "the case is going to be inspiring for people living with HIV and working in the field".

"My reservations are, it's a single case," she added.

"It's also uncertain whether the teen would have controlled (her HIV infection) without any treatment. We know 1% of people who become infected naturally control the virus and don't require treatment."

10 Important HIV/AIDS Discoveries
1. Most Don't Have Their Infection Under Control (01 of10)
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Only one quarter of the 1.1 million people with HIV have their condition under control, where "under control" means the virus has been suppressed, according to a report released this summer by the Centers for Disease Control and Prevention. CORRECTION: The first sentence has been reworded to more accurately reflect the number of people with HIV. (credit:Alamy)
2. Experiments With Bone Marrow Transplants Have Been Unsuccessful To Date(02 of10)
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Even though two men were, for a time, able to go off antiretrovirals because their HIV had been reduced to undetectable levels after receiving bone marrow transplants, the HIV eventually returned in the men, according to news reports.In 2012, the news of the men’s undetectable HIV levels made headlines. The men, who were both HIV positive and taking antiretroviral drugs, had received bone marrow transplants for Hodgkin’s lymphoma. They had received the transplants while they were also taking the antiretroviral medication. However, in late 2013, preliminary results showed that the HIV had returned. This slide has been updated to note more recent developments related to the procedure. (credit:Alamy)
3. No-Cost HIV Treatment Could Cut New Infection Rates(03 of10)
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New HIV infection rates can be dramatically lowered by making antiretroviral drugs free, a study from Canadian researchers found. The Canadian Press reported on the study, conducted by B.C. Centre for Excellence in HIV-AIDS researchers, which showed that British Columbia -- a province that offers free access to antiretroviral therapy -- had the lowest rate of new HIV infections over a more-than-10-year period, compared with Ontairio and Quebec. (credit:Alamy)
4. Many Young People Don't Know Their HIV Status (04 of10)
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More than half of HIV-infected young people are unaware that they have the virus, according to a Centers for Disease Control and Prevention report."Given everything we know about HIV and how to prevent it in 30 years of fighting the disease, it's just unacceptable that young people are becoming infected at such high rates," Reuters reported CDC Director Dr. Thomas Frieden saying. The report also showed that for young people, 72 percent of the new HIV infections were in men who have sex with men, while almost 50 percent were in young, African-American males, Reuters reported. These figures are based on 2010 data. (credit:Alamy)
5. More People Are Living With HIV Than 10 Years Ago(05 of10)
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The number of people living with HIV has increased by 18 percent from 2001 to 2011, according to a report released this year from the United Nations Programme on AIDS. An estimated 34.2 million people around the world are living with HIV. The report also showed that deaths from AIDS have dropped, from 2.3 million in 2005-2006 to 1.7 million in 2011, Reuters reported. (credit:Alamy)
6. The Cost Of HIV Drugs Is Decreasing(06 of10)
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According to the same United Nations report, costs for the cheapest UN-recommended antiretroviral therapy drugs have also decreased over the past 10 years, Reuters reported. A year's worth of the drugs used to cost $10,000 in 2000 for one person; now, it costs $100 a year. (credit:Alamy)
7. HIV Treatment Truvada Can Also Be Used As A Preventive Measure(07 of10)
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The Food and Drug Administration this year officially approved the drug Truvada -- which has been used since 2004 as a treatment for HIV -- to be sold as a preventive measure for people who don't have the infection, but are at high risk for it.The FDA said that the pill should be considered for preventive use not only by gay or bisexual men who are at high risk for HIV, but also heterosexual men and women who may also face HIV risks, the Associated Press reported. Heterosexual men and women make up more than one-fourth of new cases of HIV, and "that's not a portion of the epidemic we want to ignore," the CDC's Dr. Dawn Smith, who was the lead author of the new recommendations, told the Associated Press. The FDA also approved a new drug this year, Stribild, to treat HIV, Reuters reported. (credit:Getty Images)
8. Engineered Stem Cells Could Play A Part In Fighting HIV(08 of10)
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9. Pretty Much Everyone Should Be Screened For HIV(09 of10)
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People should be screened for HIV even if they're not at high risk of contracting the infection, according to draft recommendations released just last month by the U.S. Preventive Services Task Force. The recommendations would mean that everyone between the ages of 15 and 65 should be screened for HIV, even if they're not at high risk for it, Reuters reported. "The prior recommendations were for screening high-risk adults and adolescents," Dr. Douglas Owens, a member of the USPSTF task force and a Stanford University medical professor, told Reuters. "The current recommendation is for screening everyone, regardless of their risk." (credit:Alamy)
10. People Should Be Treated With Antiretrovirals As Soon As They're Diagnosed WIth HIV (10 of10)
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All HIV patients should be treated immediately with antiretrovirals, according to new guidelines issued this year from a panel of the International Antiviral Society-USA, as reported by TIME. The recommendations are counter to previous guidelines, which said that antiretrovirals should only be used if the CD4 count -- a measure of immune cells in a person's body -- becomes less than 350 cells for every mm3 of blood. (credit:Alamy)