New Drug Created To Reduce Harmful Effects Of Binge-Drinking | HuffPost Life

Is This The Ultimate Hangover Cure?

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A drug has been created that could reduce the harmful effects of binge-drinking on the brain, according to scientists.

Researchers believe it may also open the door to new treatments for Alzheimer's and other brain diseases.

Named ethane-beta-sultam, the drug was developed over 10 years by British, Belgian and Italian scientists.

Tested on rats experiencing the equivalent of a human binge-drinking bender, the drug curbed brain cell loss and inflammation and improved their memory.

Evidence suggests that binge-drinking may have long-term effects on memory, decision-making and the ability to pay attention. Teenagers are especially at risk because their young brains are still developing.

Binge-drinking is defined as consuming five or more alcoholic drinks one after the other over a four to six-hour period.

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Rats taking part in the study were given doses of alcohol designed to simulate binge-drinking in a human. Their memory was tested by seeing how well they could find a hidden platform in a water maze.

Animals treated with ethane-beta-sultam were able to navigate the maze as well as those not fed alcohol.

Professor Mike Page, from the University of Huddersfield, said: "One of things that alcohol does is to destroy some of the brain cells which are important for navigation and orientation.

"But a combination of alcohol and our compound could overcome this damage."

Future work may turn up a compound that performs even better than ethane-beta-sultam, he added.

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Signs Of Alcoholism

Abuse: Not Meeting Responsibilities(01 of20)

Abuse, the regular use of a substance that leads to serious psychological and/or physical disability, is shown by one or more of these symptoms during the same year:Repeated substance use to the point of not being able to meet responsibilities -- not performing well at work, being suspended from school, being repeatedly late or absent from required duties, or neglecting household tasks. (credit:Shutterstock)

Abuse: Involving Risk(02 of20)

Abuse, the regular use of a substance that leads to serious psychological and/or physical disability, is shown by one or more of these symptoms during the same year:Repeated substance use when there is risk involved, like operating equipment or driving a car while under the influence. (credit:Shutterstock)

Abuse: Difficulties With The Law(03 of20)

Abuse, the regular use of a substance that leads to serious psychological and/or physical disability, is shown by one or more of these symptoms during the same year:Repeated difficulties with the law related to substance use -- being arrested for physical aggression or drunk driving, for instance. (credit:Shutterstock)

Abuse: Personal Or Social Difficulties(04 of20)

Abuse, the regular use of a substance that leads to serious psychological and/or physical disability, is shown by one or more of these symptoms during the same year:Insisting on using the substance regardless of continued or repeated personal or social difficulties because of it, verbal or physical aggression with a loved one, or frequent arguments about the substance use. (credit:Shutterstock)

Dependence: Needing Great Amounts(05 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Needing greater amounts of alcohol to satisfy cravings. (credit:Shutterstock)

Dependence: An Inability To Reduce Use(06 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Using the substance longer than planned or more frequently and in greater amounts.An inability to reduce use, despite a sincere wish to do so. (credit:Shutterstock)

Dependence: Going Through Withdrawal(07 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Going through withdrawal when not using alcohol, with symptoms such as tremors, restlessness, and agitation. (credit:Shutterstock)

Dependence: Avoiding Withdrawal(08 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Taking a substance or a similar one to avoid the effects of withdrawal. (credit:Shutterstock)

Dependence: Spending Time On Alcohol(09 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Spending a significant amount of time trying to acquire the substance.Spending less time at work or on other activities because of substance use; a person may completely abandon previously enjoyable activities. (credit:Shutterstock)

Dependence: Drinking In The Face Of Difficulty(10 of20)

Symptoms of alcohol dependence, a physical need to drink, are identified as three or more of the following within the same year:Continuing to drink despite being aware that alcohol is causing psychological or physical difficulties. (credit:Shutterstock)

Addiction: Saying Inappropriate Things(11 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Does he/she frequently say inappropriate things? (credit:Shutterstock)

Addiction: Slurred Speech(12 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Does his/her speech slurred? (credit:Shutterstock)

Addiction: Missing Work(13 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Does he/she miss work? (credit:Shutterstock)

Addiction: Off Balance(14 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Is his/her balance off when they walk? (credit:Shutterstock)

Addiction: Trouble With The Law(15 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Has he/she gotten in trouble with the law, for example, with drinking and driving? (credit:Shutterstock)

Addiction: Health Problems(16 of20)

Stephen Gilman, MD, an addiction specialist in New York City, helps determine the severity of alcohol addiction by asking the following questions:Is he having health issues related to alcohol addiction, such as heartburn, liver problems, high blood pressure, or insomnia? (credit:Shutterstock)

Question To Ask: Should I Cut Down?(17 of20)

Take the CAGE questionnaire -- if the answer to two or more of the four CAGE questions is yes, it is likely you have a problem.C stands for cut-down: Do you ever feel that you should cut down on your drinking? (credit:Shutterstock)

Question To Ask: People Getting Annoyed?(18 of20)

Take the CAGE questionnaire -- if the answer to two or more of the four CAGE questions is yes, it is likely you have a problem.A stands for annoyed: Have people annoyed you by criticizing your drinking? (credit:Shutterstock)

Question To Ask: Ever Felt Guilty?(19 of20)

Take the CAGE questionnaire -- if the answer to two or more of the four CAGE questions is yes, it is likely you have a problem.G stands for guilty: Have you ever felt guilty about your drinking? (credit:Shutterstock)

Question To Ask: Drinking To 'Recover'?(20 of20)

Take the CAGE questionnaire -- if the answer to two or more of the four CAGE questions is yes, it is likely you have a problem.E stands for eye-opener: Have you ever had to drink as soon as you wake up to steady your nerves or get over a hangover? (credit:Shutterstock)

In the longer term, such compounds may help in the treatment of diseases such as Alzheimer's that also involve inflammation and the loss of brain cells.

Page acknowledged that protecting against the harmful effects of binge-drinking on the brain might be controversial, but added: "If you accept that alcohol abuse is going to continue, then it might be sensible for society to try and treat it in some way."

The research is published in the Journal Of Alcoholism And Drug Dependence.

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