Their new photoshoot - by legendary photographer Mario Testino - marks the 20th anniversary of the fundraising campaign. The supermodel pals both posed for its launch way back in 1996.
This year's campaign calls on British shoppers to show their support by buying an item from the 2016 Fashion Targets Breast Cancer collection, available in high street stores such as Marks & Spencer, Debenhams, River Island, Topshop and Simply Be.
Every item in the range carries a minimum 30% donation (with some items donating 100% of profits) towards pioneering research by UK charity Breast Cancer Now.
Fashion Targets Breast Cancer was originally founded by American designer Ralph Lauren in 1994, after he lost a close friend to the disease. It then launched in the UK two years later.
Over the last two decades the campaign has been supported by some of the biggest names in fashion, including Claudia Schiffer, Elle Macpherson, Twiggy and Yasmin le Bon.