Together with her best pal Holly Willoughby, Fearne has appeared as a team captain in almost every single series of the ITV2 show, taking a break in 2013 for maternity leave.
But now, she’s decided to call time for good.
Confirming the news, the former Radio 1 DJ tweeted: “After ten years on Celebrity Juice I am leaving.
“I walk away with so many incredible memories and will miss everyone in front of and behind the cameras so much. So much love and luck to them all for future series.”
Holly then posted a message on Instagram, writing: “Thank you for 10 years of laughter... love you @fearnecotton ... we are going to MISS you on @celebjuiceofficial SOOO much.”
‘Celebrity Juice’ host Host Keith Lemon added: “End of an era! Gonna miss @fearnecotton. Fanks for the fun times. Love you deeply! Good luck with your next chapter!
“I hope one day we’ll play again. But the show must go on.”
He added that the show will be back, with a new captain replacing Fearne, in March next year.
The 37-year-old’s career has come a long way since her children’s TV presenting days and she now focuses on her Radio 2 show, wellbeing podcast and books.
Fearne is also a patron for charities including CoppaFeel and The Prince’s Trust.