The comic - who writes the series, and also plays lead character Edina Monsoon - added that she thinks a film could 'ruin' the show, despite previously saying that she was 'definitely' going to do it.
"It'll never happen," she told Glamour magazine.
"We've been talking about it for so long and now I've just got this feeling that 'Ab Fab' is in such a nice place now - if we made the film there would be such a danger that we could ruin it."
Back in 2011, Jennifer had told New York magazine: "Yes, I'm definitely going to do it. I'm aiming to shoot this in a beautiful part of the Riviera. I fancy the south of France in the spring."
Her co-star Joanna Lumley - who plays Patsy Stone - also told Metro last year that she would be happy to star in a film adaptation.
The series - which aired for the first time in 1994 - returned for two specials over Christmas in 2011, with a further Olympics-themed episode airing ahead of the 2012 games.
BBC executive Shane Allen said earlier this year at the Broadcasting Press Guild Lunch that the "door is always open for more 'Ab Fab'".