David, whose hit comedy was first broadcast on the channel, urged fans to sign the Change.org petition via his Twitter account.
“If you want to #SaveBBC3 sign this petition. I am a bit biased as @bbcthree was where 'Little Britain' started!” he wrote.
With over 115k signatures and counting, the Change.org petition is the fastest-growing and biggest petition relating to a television network to ever appear on the site.
Plans to axe the channel in 2015 and make its programmes available via iPlayer only were confirmed by BBC Director-General Tony Hall yesterday afternoon.