British singer Sam shared the exciting news on Monday morning, telling his Twitter followers: “So honoured to collaborate with such an incredible artist. Please do support the track, it is for a great cause.”
John is also delighted to have been involved in the charity project, telling the BBC: “Sam is such a talented artist. We've been looking forward to working together for a while now.
"I'm so glad we could collaborate on such a great song and for such a great cause.”
All profits from the singles’ sales will go to the charity, and the duo will perform the ballad together during the Comic Relief telethon, on Friday 13 March.
Ahead of the track’s release, Sam has been seeing the work the charity completes firsthand.
"I recently visited a Comic Relief-funded project in my hometown which supports the young LGBT community in London.” he explains. "I'm extremely proud that my single will help raise money for projects like this and many others in the UK and across Africa."
Sam has previously opened up about his own personal difficulties, revealing that he faced homophobic abuse shortly after moving to London.
"When I moved to London I got punched in the neck walking back from work. It was definitely homophobic,” he explained. "I was on the phone speaking quite loudly and had pink earphones on so it was pretty clear I was gay."
Watch Sam and John’s ‘Lay Me Down’ video below...