Scientists has discovered four 'Father Time' genes that help determine how fast we age.
The ageing genes are switched on or off by environmental and lifestyle factors such as diet, and may be programmed from an early age.
Knowing how the genes are altered could pave the way to new generations of anti-ageing drugs, researchers believe.
Scientists already knew that "epigenetic" changes - chemical alterations to DNA made by external factors in the environment - are important to ageing.
The new research goes some way towards solving the riddle of how and when these effects occur.
Dr Jordana Bell, one of the study authors from King's College London, said: "We found that epigenetic changes associate with age-related traits that have previously been used to define biological age.
"We identified many age-related epigenetic changes, but four seemed to impact the rate of healthy ageing and potential longevity and we can use these findings as potential markers of ageing.
"These results can help understand the biological mechanisms underlying healthy ageing and age-related disease, and future work will explore how environmental effects can affect these epigenetic changes."
The scientists, whose work is reported in the online journal Public Library of Science Genetics, first looked for epigenetic changes in the DNA of 172 twins aged 32 to 80.
Twins are often used in such studies because identical pairs share exactly the same genes, making it possible to tease apart genetic and environmental effects. If one identical twin displays very different characteristics from the other it means the cause cannot be genetic.
Analysing the changes in relation to chronological age, the researchers identified 490 age-related epigenetic changes.
Matching these to specific age-related traits highlighted four genes displaying changes linked to cholesterol levels, lung function and maternal lifespan.
Further research showed that many of the epigenetic DNA alterations were also present in a group of 44 younger twins aged 22 to 61.
This suggests that while many age-related genetic changes caused by environmental factors occur throughout a person's life, some might be triggered early on.
Professor Tim Spector, director of the Department of Twin Research at King's College, said: "This study is the first glimpse of the potential that large twin studies have to find the key genes involved in ageing, how they can be modified by lifestyle and start to develop anti-ageing therapies.
"The future will be very exciting for age research."
Gene experts at the Wellcome Trust Sanger Institute in Hinxton, Cambridgeshire, played a key role in the study.
Sanger scientist Dr Panos Deloukas pointed out that the research was still at an early stage. "Our study interrogated only a fraction of sites in the genome (genetic code) that carry such epigenetic changes; these initial findings support the need for a more comprehensive scan of epigenetic variation," he said.
Anti-Ageing Herbs
Anti-Ageing Herbs That Protect Against Premature Ageing (01 of11)
Open Image Modal (credit:Alamy)
Milk Thistle(02 of11)
Open Image ModalMilk thistle encourages the liver to make a powerful antioxidant, which aids the regeneration of new skin cells and helps to create a glowing, youthful complexion. (credit:Flickr:aehack)
Ginseng (03 of11)
Open Image ModalGinseng is a perennial herb and its root is used to help beat age-related problems such as high blood sugar and cholesterol levels. It also helps alleviate stress, stimulates physical and mental activity, which may slack in older age, and protects the body from severe, physical pain. (credit:Flickr:missmeng)
Rhodiola Rosea(04 of11)
Open Image ModalThe Rhodiola Rosea is an 'adaptogen' herb which has long been used to enhance the body's ability to cope with mental stress. It is also believed that the herb could help protect the brain from age-related mental disorders such as Alzheimer's and enhance body stamina and strength. (credit:MediaWiki)
Rosemary(05 of11)
Open Image ModalRosemary helps to redress the skin's moisture balance, perfect for fending off sagging and wrinkles. It also helps protect the skin cells from environmental damage by aiding the development of collagen in the skin, leaving it plumper and more supple. (credit:Flickr:GlennFleishman)
Ashwagandha (06 of11)
Open Image ModalAshwagandha is thought to help with the prevention of dementia by restoring the neurotransmitters in the brain. Ashwagandha also helps the body build a resistance to stressand can be used as stimulant for a healthy immune system. (credit:Flickr:cliff1066™)
Ginkgo Biloba(07 of11)
Open Image ModalGingko Biloba contains crucial antioxidants that help to improve blood flow to the brain which help the body's peripheries function - ideal for those with poor circulation in the fingers and toes. (credit:Flickr:Joost J. Bakker IJmuiden)
Cat's Claw (08 of11)
Open Image ModalAlso known as Uña de Gato in Spanish and Vilcacora in Indian, the Cat's Claw herb's super-immune-system qualities help battle age-related problems such as high blood pressure, bad circulation and high cholesterol levels. (credit:Flickr:John Tann)
Grape Seeds(09 of11)
Open Image ModalThe seeds from the grape contain powerful antioxidants called procyanidins that neutralise damaging free radical in the joints. (credit:Flickr:Smabs Sputzer)
Pine Bark (10 of11)
Open Image ModalPine bark, also known as Pycnogenol, strengthens capillaries, arteries and veins and fights inflammation to improve joint flexibility. It also helps the body to circulate more blood during stressful conditions without increasing blood pressure or making the heart work harder. (credit:Flickr:Son of Groucho)
Reishi (11 of11)
Open Image ModalKnown as the 'mushroom of immortality' this colourful fungi has been a folk medicine in China for thousands of years. It is traditionally used to treat age-related conditions like hypertension, arthritis, insomnia and lung disorders.It is also a great anti-inflammatory agent and can be taken in the form of tea or tablets. (credit:Flickr:frankenstoen)
Bizarre Anti-Ageing Treatments
Snail Slime Cream (01 of10)
Open Image ModalEmu Oil(02 of10)
Open Image ModalRendered from from the fat of an emu bird, emu oil is a lesser known anti-ageing oil that has been used for centuries in the Aboriginal communities for its healing powers. Mixed with eucalyptus oil, it containing bundles of vitamin E and A, the oil's antioxidants help repair wounds and thickens skin against ageing. The cream also soaks moisture into the skin, which avoids dehydrated, saggy looking skin. (credit:Alamy)
Pigs Trotters(03 of10)
Open Image ModalDefinitely not one for vegetarian beauty fans, but pigs trotters are a popular anti-ageing solution in Japan, as the trotters are a great source of collagen - the vital ingredient for boosting elasticity in the skin. (credit:Alamy)
Bee Sting Venom (04 of10)
Open Image ModalThe bee sting venom facial doesn't involve a her of bees pricking your face, but instead, the venom from the sting is transferred into a gel and then rubbed on the face as part of an intensive facial. According to researchers in South Korea, the venom helps prevent the skin from sun damage and restores collagen production. (credit:Alamy)
Sperm Facial(05 of10)
Open Image ModalSpermine is a powerful antioxidant in human sperm and some beauty goers swear by its anti-ageing super powers. This treatment first surfaced in New York where the 'cream' is applied over the skin and then ultrasound and infrared light is used to penetrate through the skins lipid barrier. It's believed this 'sperm facial' leaves the skin looking blemish and wrinkle-free.And you don't have to have the treatment done in a salon, as a Norwegian company, Bioforskning, sell sperm-based products. (credit:Alamy)
Breast Milk Soap (06 of10)
Open Image ModalBreast milk soap claims to be a great alternative to ordinary soap as it doesn't dry up the skin and is good for reducing the appearance of facial scarring and wrinkles. However, the only snag is - it's best to make the soap yourself if you're breastfeeding. The ingredients? Olive oil, palm oil, coconut oil, heat-treated breast milk, and purified water. (credit:Alamy)
Anti-Sagging Lips(07 of10)
Open Image ModalBaby's Foreskin(08 of10)
Open Image Modal'Platza' Treatment (09 of10)
Open Image ModalThis alternative and somewhat painful-looking anti-ageing massage is designed to stimulate the blood flow, creating a youthful glow.The 'platza' treatment involves the bare back being thwarted with a 'broom' made of oak-leaf branches. The harsh brushing technique is also said to help tone up muscles and invigorate sluggish energy levels. (credit:Flickr)
Placenta Cream(10 of10)
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