High Levels Of Ceramides Fat In The Blood ‘Increases Alzheimer's Risk'

Could A Simple Blood Test Predict Alzheimer’s Risk?

Researchers claim they have identified a new indicator (or ‘biomarker’) in the blood that may help health experts predict a person’s risk of Alzheimer’s disease.

The small study by the Mayo Clinic, based in the US, tested the blood of 99 women aged 70 to 79 for levels of a fatty compound called ceramides.

Open Image Modal

Could a blood test predict your risk of Alzheimer's?

The participants were placed into three groups: high, middle and low levels of ceramides.

Over the nine-year study, 27 women developed dementia and 18 were diagnosed with ‘probable’ Alzheimer’s disease.

A follow-up found that women with the highest levels of fat in their blood were 10 times more likely to develop Alzheimer’s disease than those with lower amounts of the blood biomarker.

Women with ‘middle’ levels were eight times more at risk of dementia.

"Our study identifies this biomarker as a potential new target for treating or preventing Alzheimer's disease," says lead study author Michelle Mielke in a statement issued by the American Academy of Neurology.

"These findings are important because identifying an accurate biomarker for early Alzheimer's that requires little cost and inconvenience to a patient could help change our focus from treating the disease to preventing or delaying it," adds Valort Pavlik from the Alzheimer's Disease and Memory Disorders Center of Baylor College of Medicine.

Pavlik adds: "While a larger, more diverse study is needed to confirm these findings, projections that the global prevalence of Alzheimer's disease will double every 20 years for the foreseeable future.

"This increased the sense of urgency among researchers and health care agencies to identify more effective screening, prevention and treatment strategies."

Ways To Beat Dementia
Lifestyle Changes To Help Prevent Dementia(01 of07)
Open Image Modal
(credit:Alamy)
Drink Decaffeinated Coffee(02 of07)
Open Image Modal
A study at Mount Sinai School of Medicine found that decaffeinated coffee improves the brain's energy metabolism - linked to cognitive decline - in those with Type 2 diabetes."This is the first evidence showing the potential benefits of decaffeinated coffee preparations for both preventing and treating cognitive decline caused by type 2 diabetes, ageing, and/ or neurodegenerative disorders," said lead researcher, Dr Giulio Maria Pasinett. (credit:Alamy)
Play Brain-Teasing Games(03 of07)
Open Image Modal
Everyday games, puzzles and tasks were able to postpone decline in cognitive function and the ability to carry out everyday tasks, in dementia patients, for at least a year, according to research from the University of Erlangen in Germany, published in the journals BMC Medicine. (credit:Alamy)
Eat Less(04 of07)
Open Image Modal
Eating fewer calories could help boost memory and cognitive function, according to a study at the Catholic University of the Sacred Heart in Rome. Researchers hope to mimic the same effect with a drug in the future, bringing hope to Alzheimer's sufferers as well as those suffering from injury-related memory loss. (credit:Alamy)
Eat Fish(05 of07)
Open Image Modal
Researchers at the University of Pittsburgh Medical Centre and School of Medicine found that people who ate baked or grilled fish regularly reduced their risk of developing Alzheimer's.Reseracher Cyrus Raji said: "The results showed that people who consumed baked or broiled (grilled) fish at least one time per week had better preservation of grey matter volume on MRI in brain areas at risk for Alzheimer's disease." (credit:Alamy)
Play The Wii Fit(06 of07)
Open Image Modal
Working out using virtual games such as the Wii Fit could slow cognitive decline in the over 50s, researchers from Union College in the US found.Participants aged between 58 and 99 were given a 3D exercise game to play. Compared to the control group who were asked to use a regular exercise bike, the 'cybercycle' group had a 23% decrease in advancement of mild cognitive impairment and showed improved 'executive function'. (credit:Alamy)
Do The Seven-Step Plan(07 of07)
Open Image Modal
A study in The Lancet Neurology suggest that 3m cases of Alzheimer's across the world could be prevented in seven simple ways. The report recommends quitting smoking, increasing physical activity, controlling your blood pressure and diabetes risk factors as well as managing depression and obesity to help combat the disease. (credit:Alamy)