Woman's Pregnancy Hope After Receiving Frozen Ovary Taken From Her Body Before Puberty

"I want to believe I will be pregnant."
|

A woman who had her ovary removed and frozen as a child has had the organ implanted back into her body so she can become a mother.

If the transplant proves successful and she falls pregnant, Moaza Alnatrooshi will be the first woman in the world to conceive using an ovary frozen before puberty and transplanted back into the body.

Alnatrooshi told the Sunday Times that nothing made her happier than using her own ovary to try and have a baby.

She added: "I want to believe I will be pregnant. I cannot wait for that day."

Open Image Modal
William Andrew via Getty Images

Alnatrooshi, 23, from Dubai, had her ovary removed and frozen when she was just eight years old after being diagnosed with a blood disorder called beta thalassaemia.

To treat the illness, she had chemotherapy followed by a bone marrow transplant.

However because chemotherapy can cause damage to the ovaries, specialists removed and froze one of Alnatrooshi's ovaries in the hope that she would one day be able to have children. 

Last year, Alnatrooshi’s frozen ovary was sent from London to Denmark, where it was transplanted back into her body. 

Alnatrooshi and her husband have since undergone IVF treatment in a bid to get pregnant. Eight eggs were collected and three embryos have been produced.

One of the embryos is expected to be implanted next month and doctors have said they are confident that Alnatrooshi will fall pregnant because of her age.

The 23-year-old shared a message for other women affected by infertility, telling them not to give up.

She said: "I would like to say to all women that they have got to have hope."

Her gynaecologist, Dr Sara Matthews from the Portland Hospital for women and children, said the treatment had huge potential to help young girls who develop cancer or other conditions which require chemotherapy to one day have their own children.

In November 2014, a 27-year-old woman gave birth to a healthy baby boy after undergoing an ovarian tissue transplant.

Her ovary had originally been removed and frozen when she was 13 years old, during puberty. 

If Alnatrooshi's ovary, which was taken prior to puberty, helps her fall pregnant then it will be a huge step forward for girls affected by cancer at a young age. 

Professor Geeta Nargund, medical director of Create Fertility, told The Huffington Post UK: "If this is successful, it would be a breakthrough to help pre-pubertal girls diagnosed with cancer to preserve their fertility.

"Ovarian freezing and transplantation is still an experimental technique and we need further large studies.

"Women in reproductive years diagnosed with cancer can freeze their eggs or embryos prior to cancer treatment to preserve their fertility. This is available on NHS and has proven successful.

"However, for pre-pubertal girls who are unable to freeze eggs, ovarian tissue freezing can be the only option to preserve their future fertility." 

10 Things You May Not Know About Your Fertility
(01 of10)
Open Image Modal
1. Your fertility is mostly determined by genetics, which influences how many eggs you are born with. Doctors believe that the number of eggs you have at birth determines the length of time you will remain fertile. At birth, women have about two million eggs in their ovaries. For every egg ovulated during your reproductive life, about 1,000 eggs undergo programmed cell death. Other things, such as smoking cigarettes and certain types of chemotherapy, can accelerate egg cell death and promote an earlier menopause.
(02 of10)
Open Image Modal
2. Regular menstrual cycles are a sign of regular ovulation.Most women have regular cycles lasting between 24 and 35 days. This is usually a sign of regular, predictable ovulation. Women who do not ovulate regularly have irregular menstrual cycles. Those who do not ovulate at all may have a genetic condition called polycystic ovarian syndrome (PCOS).
(03 of10)
Open Image Modal
3. Basal temperature charting does not predict ovulation.An older method of tracking ovulation involves taking your oral body temperature each morning before getting out of bed. This is called basal body temperature. This method is used to spot a rise in basal temperature, which is a sign that progesterone is being produced. The main problem with using this method is that your temperature rises after ovulation has already occurred. This makes it more difficult to time intercourse at an optimal time for conception. A better method is to use over-the-counter urine ovulation predictor test kits such as Clearblue Easy. These kits test for the hormone that prompts ovulation, which is called luteinizing hormone (LH).
(04 of10)
Open Image Modal
4. Most women with blocked fallopian tubes are completely unaware they may have had a prior pelvic infection.About 10 percent of infertility cases are due to tubal disease, either complete blockage or pelvic scarring causing tubal malfunction. One major cause of tubal disease is a prior pelvic infection from a sexually transmitted disease such as chlamydia. These infections can cause so few symptoms that you may be completely unaware your tubes are affected. This is why fertility physicians will order a dye test of the tubes, called a hysterosalpingogram (HSG), if you have been trying and failing to conceive for 6 months or longer.
(05 of10)
Open Image Modal
5. In most cases, stress does not cause infertility. Except in rare cases of extreme physical or emotional distress, women will keep ovulating regularly. Conceiving while on vacation is likely less about relaxation than about coincidence and good timing of sex.
(06 of10)
Open Image Modal
6. By age 44, most women are infertile, even if they are still ovulating regularly. Even with significant fertility treatment, rates of conception are very low after age 43. Most women who conceive in their mid-40s with fertility treatment are using donated eggs from younger women.
(07 of10)
Open Image Modal
7. Having fathered a pregnancy in the past does not guarantee fertility. Sperm counts can change quite a bit with time, so never assume that a prior pregnancy guarantees fertile sperm. Obtaining a semen analysis is the only way to be sure the sperm are still healthy!
(08 of10)
Open Image Modal
8. For the most part, diet has little or nothing to do with fertility. Despite popular press, there is little scientific data showing that a particular diet or food promotes fertility. One limited study did suggest a Mediterranean diet with olive oil, fish and legumes may help promote fertility.
(09 of10)
Open Image Modal
9. Vitamin D may improve results of fertility treatments. A recent study from the University of Southern California suggested that women who were undergoing fertility treatments, but had low vitamin D levels, might have lower rates of conception. This vitamin is also essential during pregnancy. At Pacific Fertility Center, we recommend our patients take 2,000-4,000 IU per day.
(10 of10)
Open Image Modal
10. Being either underweight or overweight is clearly linked with lowered levels of fertility. The evidence in recent years is that obesity is clearly linked with a longer time to conception. Having a body mass index less than 18 or over 32 is associated with problems ovulating and conceiving, as well as problems during pregnancy.

Before You Go